Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27202089 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TSHRUSP2HSD17B10HTR6 | |
| SCHEMBL27202066 | 0.79 | ALDH1A1 (0.51) | ALDH1A1TSHRUSP2HSD17B10HTR6 | |
| SCHEMBL27202087 | 0.74 | ALDH1A1 (0.54) | ALDH1A1TSHRUSP2HSD17B10HTR6 | |
| SCHEMBL27202075 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHRUSP2HSD17B10HTR6 | |
| SCHEMBL27206992 | 0.71 | ADRB1 (0.38) | ALDH1A1TSHRUSP2HSD17B10ACVR1 | |
| SCHEMBL27202080 | 0.71 | ALDH1A1 (0.43) | ALDH1A1TSHRUSP2HSD17B10HTR6 | |
| SCHEMBL27202056 | 0.70 | ACVR1 (0.41) | ACVR1IRAK4ADRB1 | |
| SCHEMBL27202055 | 0.70 | HTR6 (0.50) | ALDH1A1TSHRUSP2HSD17B10HTR6 | |
| SCHEMBL2486805 | 0.68 | ALDH1A1 (0.47) | ALDH1A1TSHRUSP2HSD17B10HTR6 | |
| Phenylpiperazine SCHEMBL29235064 | 0.68 | TSHR (0.69) | ALDH1A1TSHRUSP2HSD17B10HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | MGMT, MCL1, FANCF | ALDH1A1 446/4885TSHR 3360/4885USP2 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.