SCHEMBL27213335

SCHEMBL27213335

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NCCCC[C@@H](C(=O)NCCC(=O)N[C@H](C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1)C(C)C)N(CC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ EPOR P19235 8/20 0.35
▸ FAP Q12884 3/20 0.34
▸ MAP1LC3B Q9GZQ8 2/20 0.34
▸ SIRT2 Q8IXJ6 3/20 0.33
▸ SIRT1 Q96EB6 2/20 0.33
▸ FURIN P09958 2/20 0.33
▸ SIRT5 Q9NXA8 1/20 0.32
▸ FOLH1 Q04609 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27231233 0.88 FAP (0.35) EPORFAPMAP1LC3BSIRT2SIRT1
SCHEMBL30874648 0.88 TLR2 (0.41) SIRT2SIRT1SIRT5
SCHEMBL27213475 0.85 SIRT2 (0.36) SIRT2SIRT1FURINSIRT5
SCHEMBL27148471 0.83 FURIN (0.34) FAPMAP1LC3BSIRT2SIRT1FURIN
SCHEMBL19681567 0.82 FURIN (0.39) FAPMAP1LC3BFURINSIRT5
SCHEMBL30992313 0.81 CASP3 (0.40) SIRT2SIRT1SIRT5
SCHEMBL21738589 0.81 CASP3 (0.40) SIRT2SIRT1SIRT5
SCHEMBL21738670 0.81 CASP3 (0.40) SIRT2SIRT1SIRT5
SCHEMBL29077855 0.81 FURIN (0.36) FAPMAP1LC3BSIRT2SIRT1FURIN
SCHEMBL23880545 0.80 TLR2 (0.39) FAPMAP1LC3BFURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4548937-A1 ANTIBODY-DRUG COMPLEX Eisai R&D Management Co., Ltd. (JP) 2025-05-07 — — EP disclosed
US-20240148895-A1 ANTIBODY-DRUG CONJUGATE EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148895-A1 ANTIBODY-DRUG CONJUGATE ANTXR2, FCGR1A, HAX1 EPOR 992/4885FAP 4440/4885MAP1LC3B 1332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback