Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.70 |
| ▸ | GAA | P10253 | 10/20 | 0.70 |
| ▸ | MAPT | P10636 | 10/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19380432 | 0.73 | MAPT (0.97) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL3633562 | 0.71 | KDM4E (0.65) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL14119898 | 0.70 | LMNA (1.00) | KDM4EALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL5997551 | 0.68 | KDM4D (0.98) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL14574194 | 0.68 | MAPT (0.69) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL5992705 | 0.68 | KDM4D (1.00) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL20866608 | 0.66 | ALDH1A1 (0.64) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL9613368 | 0.64 | PTPN7 (1.00) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL11070928 | 0.64 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL14186865 | 0.64 | MAPT (0.60) | KDM4EGAAMAPTL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140080824-A1 | STRUCTURE-GUIDED IDENTIFICATION OF BINDING INTERACTIONS OF HUMAN LAMININ RECEPTOR PRECURSOR WITH LAMININ AND IDENTIFICATION OF COMPOUNDS THAT AFFECT BINDING | NEW YORK UNIVERSITY (US) | 2014-03-20 | — | — | US | claimed |
| WO-2012054739-A2 | STRUCTURE-GUIDED IDENTIFICATION OF BINDING INTERACTIONS OF HUMAN LAMININ RECEPTOR PRECURSOR WITH LAMININ AND IDENTIFICATION OF COMPOUNDS THAT AFFECT BINDING | NEW YORK UNIVERSITY (US) | 2012-04-26 | — | — | WO | claimed |
| US-20140080824-A1 | STRUCTURE-GUIDED IDENTIFICATION OF BINDING INTERACTIONS OF HUMAN LAMININ RECEPTOR PRECURSOR WITH LAMININ AND IDENTIFICATION OF COMPOUNDS THAT AFFECT BINDING | NEW YORK UNIVERSITY (US) | 2014-03-20 | — | — | US | disclosed |
| WO-2012054739-A2 | STRUCTURE-GUIDED IDENTIFICATION OF BINDING INTERACTIONS OF HUMAN LAMININ RECEPTOR PRECURSOR WITH LAMININ AND IDENTIFICATION OF COMPOUNDS THAT AFFECT BINDING | NEW YORK UNIVERSITY (US) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080824-A1 | STRUCTURE-GUIDED IDENTIFICATION OF BINDING INTERACTIONS OF HUMAN LAMININ RECEPTOR PRECURSOR WITH LAMININ AND IDENTIFICATION OF COMPOUNDS THAT AFFECT BINDING | LAMTOR3, L1CAM, AGER | KDM4E 3956/4885ALDH1A1 3214/4885GAA 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.