Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 8/20 | 0.35 |
| ▸ | WNT3A | P56704 | 8/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989536 | 0.89 | MMP1 (0.43) | MMP1THRATHRBALOX5PTGS1 | |
| SCHEMBL20914845 | 0.81 | TPMT (0.42) | KIF11 | |
| SCHEMBL4085923 | 0.75 | KMT2A (0.53) | KMT2ACYP1A2CYP2C19MEN1 | |
| SCHEMBL27250295 | 0.75 | GSK3B (0.56) | CES2MAPT | |
| SCHEMBL27250293 | 0.72 | KIF11 (0.51) | KIF11CES2 | |
| SCHEMBL13550130 | 0.72 | RAPGEF4 (0.38) | CES2P2RX1 | |
| SCHEMBL9861093 | 0.71 | ALOX5 (0.65) | THRATHRBALOX5PTGS1PTGS2 | |
| SCHEMBL30989543 | 0.70 | CES2 (0.64) | MMP1CTNNB1WNT3ACES2P2RX1 | |
| SCHEMBL16284312 | 0.70 | KMT2A (0.39) | THRATHRBPTGS1KMT2ACYP1A2 | |
| SCHEMBL27250053 | 0.69 | CES2 (0.52) | MMP1CTNNB1WNT3ACES2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024094566-A1 | INDACENE AND AZAINDACENE COMPOUNDS AND HIGHER HOMOLOGUES AND THE USE THEREOF | Credoxys GmbH (DE) | 2024-05-10 | — | — | WO | disclosed |