Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | STAMBP | O95630 | 1/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27527104 | 0.86 | KMO (0.48) | KMOASAH1KDM4ERAB9ANPC1 | |
| SCHEMBL4300707 | 0.72 | NPC1 (0.56) | KMOKDM4ERAB9ANPC1POLB | |
| SCHEMBL27339784 | 0.67 | NOTUM (0.50) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31443161 | 0.65 | ALDH1A1 (0.44) | KDM4ERAB9APOLBHSD17B10SMN1; SMN2 | |
| SCHEMBL8767297 | 0.65 | NPC1 (0.38) | KMOASAH1KDM4ERAB9ANPC1 | |
| SCHEMBL8767289 | 0.65 | KMO (0.53) | KMOKDM4ERAB9ANPC1POLB | |
| SCHEMBL27373171 | 0.64 | ALOX5 (0.45) | KDM4ESMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL2594606 | 0.64 | KMO (0.59) | KMOKDM4ERAB9ANPC1POLB | |
| SCHEMBL4048871 | 0.64 | ELANE (0.52) | KMOASAH1RAB9ANPC1POLB | |
| SCHEMBL9764205 | 0.64 | ALDH1A1 (0.47) | KMOASAH1KDM4ERAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1025855-C | Process and intermediates for prepation of oxophthalazinyl acetic acids and analogs thereof | PFIZER (US) | 1994-09-07 | — | — | CN | disclosed |
| CN-1047499-A | The method and the intermediate that prepare oxo phthalazinyl acetate and homologue | PFIZER (US) | 1990-12-05 | — | — | CN | disclosed |