SCHEMBL272985

SCHEMBL272985

O=C1C=CC=C(C=Cc2ccccc2)C1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 2/20 0.42
MAOB P27338 4/20 0.41
MAOA P21397 3/20 0.41
CYP19A1 P11511 1/20 0.41
LMNA P02545 3/20 0.36
ALDH1A1 P00352 3/20 0.36
ALOX5 P09917 2/20 0.36
NFE2L2 Q16236 1/20 0.36
TRPA1 O75762 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP1A2 P05177 2/20 0.35
MAPT P10636 2/20 0.35
HDAC3 O15379 1/20 0.35
TNKS O95271 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4324588 0.69 CMA1 (0.48) CMA1MAOBMAOACYP19A1LMNA
SCHEMBL7918809 0.69 SMN1; SMN2 (0.37) MAOBMAOACYP19A1LMNAALDH1A1
(Z)-1,2-Diphenylethene SCHEMBL27291633 0.68 MAOB (0.52) CMA1MAOBMAOACYP19A1LMNA
(Z)-1,2-Diphenylethene SCHEMBL272984 0.68 MAOB (0.52) CMA1MAOBMAOACYP19A1LMNA
(Z)-1,2-Diphenylethene SCHEMBL27546992 0.67 MAOB (0.67) CMA1MAOBMAOACYP19A1LMNA
SCHEMBL11286663 0.67 ALDH1A1 (0.50) MAOBMAOACYP19A1ALDH1A1ALOX5
(Z)-1,2-Diphenylethene SCHEMBL9134305 0.67 MAOB (0.73) MAOBMAOACYP19A1LMNAALDH1A1
(Z)-1,2-Diphenylethene SCHEMBL347707 0.67 MAOB (0.73) MAOBMAOACYP19A1LMNAALDH1A1
(Z)-1,2-Diphenylethene SCHEMBL21847984 0.67 MAOB (0.73) MAOBMAOACYP19A1LMNAALDH1A1
(Z)-1,2-Diphenylethene SCHEMBL22712863 0.67 MAOB (0.73) MAOBMAOACYP19A1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118652626-A Super-amphiphobic coating metal composite material based on three-layer structure and preparation method thereof 华中科技大学 2024-09-17 CN claimed
CN-111108443-B Electrophotographic photoreceptor, method for producing the same, and electrophotographic apparatus 富士电机株式会社 2024-01-02 CN claimed
CN-110832403-B Electrophotographic photoreceptor, method for producing the same, and electrophotographic apparatus 富士电机株式会社 2023-09-22 CN claimed
CN-111108443-A Electrophotographic photoreceptor, method for producing electrophotographic photoreceptor, and electrophotographic apparatus 富士电机株式会社 2020-05-05 CN claimed
CN-110832403-A Electrophotographic photoreceptor, method for producing the same, and electrophotographic apparatus 富士电机株式会社 2020-02-21 CN claimed
US-8133482-B2 Conjugate comprising substrate linked to cell death protease recognition sequence, photoactivatable killing agent and quencher; decontaminating blood, treating cancer or viral infections THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2012-03-13 US claimed
US-20080193431-A1 ACTIVATABLE PHOTODYNAMIC THERAPY AGENTS UNIVERSITY OF PENNSYLVANIA (US) 2008-08-14 US claimed
WO-2005048944-A2 ACTIVATABLE PHOTODYNAMIC THERAPY AGENTS UNIVERSITY OF PENNSYLVANIA (US) 2005-06-02 WO claimed
CN-117343770-B Dielectric fluid comprising natural bio-derived oil with increased stability 嘉吉公司 2026-05-19 CN disclosed
US-20260099102-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS INCLUDING THE SAME SHARP KK (JP) 2026-04-09 US disclosed
CN-112305877-B Electrophotographic photoreceptor, method for producing the same, and electrophotographic apparatus equipped with the same 富士电机株式会社 2025-05-13 CN disclosed
US-12259681-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2025-03-25 US disclosed
CN-116884670-B Synthetic esters and mineral oil dielectric fluids with increased stability 嘉吉公司 2025-02-18 CN disclosed
CN-119486870-A Recyclable multilayer structure for fluid transport, distribution or storage applications 阿科玛法国公司 2025-02-18 CN disclosed
US-4098830-A OXIDATIVE COUPLING OF ALKYLPHENOLS OR 1-NAPHTHOLS CATALYZED BY METAL COMPLEXES OF DICARBOXYLIC ACID COMPOUNDS ICI AMERICAS INC. (US) 1978-07-04 US disclosed
US-4097461-A Oxidative coupling of alkylphenols or 1-naphthols catalyzed by metal complexes of diketo compounds ICI AMERICAS INC. (US) 1978-06-27 US disclosed
US-4096190-A Oxidative coupling of alkylphenols catalyzed by metal ammonia complexes ICI AMERICAS INC. (US) 1978-06-20 US disclosed
US-4085124-A Oxidative coupling of alkylphenols, alkoxyphenols and 1-naphthols catalyzed by metal complexes of amino compounds ICI AMERICAS INC. (US) 1978-04-18 US disclosed
US-4070383-A COPPER COMPOUND-ANIONIC SURFACTANT-ALKALI METAL COMPOUND CATALYST SYSTEM ICI AMERICAS INC. (US) 1978-01-24 US disclosed
US-4067890-A Oxidative coupling of alkylphenols, alkoxyphenols and naphthols catalyzed by metal complexes of amino carboxylic and amino sulfonic acids ICI AMERICA INC. (US) 1978-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080193431-A1 ACTIVATABLE PHOTODYNAMIC THERAPY AGENTS HMBS, CD47, APEX1 CMA1 2467/4885MAOB 1147/4885MAOA 669/4885
US-20260099102-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS INCLUDING THE SAME SLC9A1, NR2E3, SLC9A2 CMA1 3444/4885MAOB 3689/4885MAOA 3526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.