SCHEMBL2730007

SCHEMBL2730007

C=CCSCCC(O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 6/20 0.40
KDM4A O75164 2/20 0.40
KDM4C Q9H3R0 2/20 0.40
KDM2A Q9Y2K7 2/20 0.40
TET3 O43151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
ALOX5 P09917 1/20 0.39
GPR84 Q9NQS5 3/20 0.35
FFAR1 O14842 1/20 0.35
OR51E2 Q9H255 1/20 0.34
TET1 Q8NFU7 1/20 0.33
BHMT Q93088 4/20 0.32
BHMT2 Q9H2M3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL721101 0.79 GPR84 (0.50) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL3435788 0.78 BHMT (0.55) BHMTBHMT2
SCHEMBL15285691 0.78 BHMT (0.55) BHMTBHMT2
SCHEMBL10639397 0.78 GABRR1 (0.42) SMN1; SMN2ALOX5BHMTBHMT2
SCHEMBL15285694 0.78 BHMT (0.55) BHMTBHMT2
SCHEMBL32674538 0.78 ALOX5 (0.33) SMN1; SMN2ALOX5
Malic Acid SCHEMBL11198944 0.75 SMN1; SMN2 (0.48) TET2TET3SMN1; SMN2ALOX5TET1
Malic Acid SCHEMBL11198947 0.75 SMN1; SMN2 (0.48) TET2TET3SMN1; SMN2ALOX5TET1
SCHEMBL10636270 0.73 SLC1A3 (0.41) SMN1; SMN2ALOX5BHMTBHMT2
SCHEMBL27028961 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3257969-B1 ETCHING LIQUID AND ETCHING METHOD MEC CO LTD (JP) 2020-04-22 EP claimed
JP-6316557-A None JP disclosed
EP-3257969-B1 ETCHING LIQUID AND ETCHING METHOD MEC CO LTD (JP) 2020-04-22 EP disclosed
US-20200109475-A1 ETCHING METHOD MEC COMPANY LTD. (JP) 2020-04-09 US disclosed
US-10358663-B2 Method of production of 2,4-dihydroxybutyric acid ADISSEO FRANCE S.A.S. (FR) 2019-07-23 US disclosed
US-20180044801-A1 ETCHING LIQUID AND ETCHING METHOD MEC CO LTD (JP) 2018-02-15 US disclosed
EP-3257969-A1 ETCHING LIQUID AND ETCHING METHOD MEC COMPANY LTD. (JP) 2017-12-20 EP disclosed
EP-2633038-B1 A METHOD OF PRODUCTION OF 2,4-DIHYDROBUTYRIC ACID ADISSEO FRANCE SAS (FR) 2017-04-05 EP disclosed
US-20160153013-A1 METHOD OF PRODUCTION OF 2,4-DIHYDROXYBUTYRIC ACID ADISSEO FRANCE SAS (FR) 2016-06-02 US disclosed
US-9238829-B2 Method of production of 2,4-dihydroxybutyric acid ADISSEO FRANCE S.A.S. (FR) 2016-01-19 US disclosed
US-8822706-B2 Method for preparing 2-hydroxybutyrolactone ADISSEO FRANCE S.A.S. (FR) 2014-09-02 US disclosed
US-20130273623-A1 NOVEL METHOD OF PRODUCTION OF 2,4-DIHYDROXYBUTIC ACID ADISSEO FRANCE S.A.S. (FR) 2013-10-17 US disclosed
EP-2633038-A1 A METHOD OF PRODUCTION OF 2,4-DIHYDROXYBUTYRIC ACID Adisseo France S.A.S. (FR) 2013-09-04 EP disclosed
US-20130204016-A1 METHOD FOR PREPARING 2-HYDROXYBUTYROLACTONE ADISSEO FRANCE S.A.S. (FR) 2013-08-08 US disclosed
WO-2012056318-A1 A METHOD OF PRODUCTION OF 2,4-DIHYDROXYBUTYRIC ACID ADISSEO FRANCE S.A.S. (FR) 2012-05-03 WO disclosed
EP-2066798-B1 PROCESS FOR THE PREPARATION OF 2-HYDROXY CARBOXYLIC ACIDS EMPLOYING BACTERIA OF THE GENUS PSEUDOMONAS, RHODOCOCCUS OR BACILLUS SUMITOMO CHEMICAL CO (JP) 2010-12-29 EP disclosed
US-20090318715-A1 Method for the Production of D,L-2-Hydroxy-4-Alkylthio Butyric Acid EVONIK DEGUSSA GMBH (DE) 2009-12-24 US disclosed
JP-H06316557-A ALKYLTHIOFATTY ACID DERIVATIVE AND ITS PRODUCTION, AND AGENT FOR HEPATIC DISEASE, KIDNEY DISEASE, PANCREATIC DISEASE AND CEREBRAL DISEASE FUJI KAGAKU KOGYO KK 1994-11-15 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130204016-A1 METHOD FOR PREPARING 2-HYDROXYBUTYROLACTONE OXSR1, CBR3, OXER1 TET2 1114/4885KDM4A 1086/4885KDM4C 959/4885
US-20090318715-A1 Method for the Production of D,L-2-Hydroxy-4-Alkylthio Butyric Acid HSD17B12, ABAT, GABBR2 TET2 1173/4885KDM4A 2878/4885KDM4C 2734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.