SCHEMBL721101

SCHEMBL721101

CCSCCC(O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.50
FFAR1 O14842 1/20 0.50
TSHR P16473 1/20 0.46
TET2 Q6N021 3/20 0.46
KDM4A O75164 2/20 0.46
KDM4C Q9H3R0 2/20 0.46
KDM2A Q9Y2K7 2/20 0.46
TET3 O43151 1/20 0.46
METAP2 P50579 4/20 0.41
METAP1 P53582 2/20 0.41
OR51E2 Q9H255 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
BHMT Q93088 2/20 0.38
BHMT2 Q9H2M3 1/20 0.38
CHRM1 P11229 1/20 0.37
AKR1A1 P14550 1/20 0.37
CHRM3 P20309 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
ADRA1A P35348 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL723058 0.86 GPR84 (0.57) GPR84FFAR1TSHRTET2KDM4A
SCHEMBL723123 0.86 GPR84 (0.52) GPR84FFAR1TET2KDM4AKDM4C
SCHEMBL724235 0.85 GPR84 (0.61) GPR84FFAR1TSHRTET2KDM4A
SCHEMBL4953418 0.83 TSHR (0.48) GPR84FFAR1TSHRMETAP2METAP1
SCHEMBL4951710 0.83 GPR84 (0.59) GPR84FFAR1TSHRTET2KDM4A
SCHEMBL24363482 0.82 METAP2 (0.40) GPR84FFAR1TSHRMETAP2METAP1
SCHEMBL12502961 0.82 TSHR (0.39) GPR84FFAR1TSHRMETAP2METAP1
SCHEMBL18832143 0.81 GPR84 (0.62) GPR84FFAR1BHMT
SCHEMBL18832138 0.80 GPR84 (0.66) GPR84FFAR1BHMT
SCHEMBL18832145 0.80 GPR84 (0.66) GPR84FFAR1BHMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116924950-A Preparation method of 2-hydroxy-4-substituted thiobutyric acid and derivatives thereof 元素驱动(杭州)生物科技有限公司 2023-10-24 CN disclosed
CN-106795511-B Oxidase, polynucleotide encoding the same, and use thereof 住友化学株式会社 2020-02-11 CN disclosed
CN-106661571-B Oxidase, polynucleotide encoding the same, and use thereof 住友化学株式会社 2019-12-20 CN disclosed
EP-3168301-B1 OXIDASE, POLYNUCLEOTIDE ENCODING SAME, AND USE OF THESE SUMITOMO CHEMICAL CO (JP) 2019-11-20 EP disclosed
US-10364448-B2 Method for producing L-α-amino acid compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-07-30 US disclosed
US-10351829-B2 Oxidase, polynucleotide that codes for same, and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-07-16 US disclosed
US-20170191097-A1 OXIDASE, POLYNUCLEOTIDE ENCODING SAME, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-06 US disclosed
US-20170159029-A1 OXIDASE, POLYNUCLEOTIDE THAT CODES FOR SAME, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
EP-3168302-A1 OXIDASE, POLYNUCLEOTIDE THAT CODES FOR SAME, AND USES FOR BOTH Sumitomo Chemical Company, Limited (JP) 2017-05-17 EP disclosed
EP-3168301-A1 OXIDASE, POLYNUCLEOTIDE ENCODING SAME, AND USE OF THESE Sumitomo Chemical Company, Limited (JP) 2017-05-17 EP disclosed
WO-2012026620-A1 PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 WO disclosed
US-7465471-B2 Palatability of aquaculture feed NOVUS INTERNATIONAL, INC. (US) 2008-12-16 US disclosed
WO-2007147155-A1 POLYOL ESTER COMPOUNDS NOVUS INTERNATIONAL INC. (US) 2007-12-21 WO disclosed
US-20070292485-A1 POLYOL ESTER COMPOUNDS NOVUS INTERNATIONAL INC. (US) 2007-12-20 US disclosed
US-20050215623-A1 Palatability of aquaculture feed NOVUS INTERNATIONAL, INC. (US) 2005-09-29 US disclosed
EP-1531672-A2 ANTIMICROBIAL COMPOSITIONS Novus International, Inc. (US) 2005-05-25 EP disclosed
US-20040175434-A1 Antimicrobial compositions NOVUS INTERNATIONAL, INC. 2004-09-09 US disclosed
WO-2004019683-A2 ANTIMICROBIAL COMPOSITIONS NOVUS INTERNATIONAL, INC. (US) 2004-03-11 WO disclosed
US-5973200-A FREE RADICAL ADDITION OF METHYL MERCAPTAN TO A NONCONJUGATED OLEFINIC SUBSTRATE HAVING A TERMINAL CARBON-CARBON DOUBLE BOND NOVUS INTERNATIONAL, INC. (US) 1999-10-26 US disclosed
WO-1999008992-A1 2,4-PENTADIENOIC ACID DERIVATIVES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY ALLERGAN SALES, INC. (US) 1999-02-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070292485-A1 POLYOL ESTER COMPOUNDS PNLIP, ELOVL1, ELOVL5 GPR84 1794/4885FFAR1 204/4885TSHR 4149/4885
US-10351829-B2 Oxidase, polynucleotide that codes for same, and use thereof DAO, PNPO, HAO1 GPR84 4093/4885FFAR1 2509/4885TSHR 4623/4885
US-20050215623-A1 Palatability of aquaculture feed TAS2R3, TAS2R1, TAS2R20 GPR84 893/4885FFAR1 747/4885TSHR 1282/4885
US-20040175434-A1 Antimicrobial compositions MRPL21, FPR1, ARG1 GPR84 4587/4885FFAR1 2240/4885TSHR 4028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.