SCHEMBL2731366

SCHEMBL2731366

C=CCC(=O)OCCn1c(=O)n(C)c(=O)n(CCO)c1=O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.36
HTT P42858 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ADORA2B P29275 1/20 0.33
ALDH1A1 P00352 1/20 0.32
PLA2G4A P47712 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP3A4 P08684 1/20 0.31
POLB P06746 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2367695 0.88 HTT (0.42) GAAHTTKDM4EADORA2BALDH1A1
SCHEMBL2732955 0.87 TSHR (0.38) GAAHTTKDM4EADORA2BALDH1A1
SCHEMBL2730490 0.82 TSHR (0.49) GAAKDM4EADORA2BALDH1A1CYP3A4
SCHEMBL2730786 0.75 TSHR (0.46) GAAHTTKDM4EADORA2BALDH1A1
SCHEMBL776295 0.75 TSHR (0.55) GAAALDH1A1PLA2G4AMEN1KMT2A
SCHEMBL230828 0.75 TSHR (0.55) GAAALDH1A1PLA2G4AMEN1KMT2A
SCHEMBL2730449 0.74 PDE4A (0.41) HTTKDM4EADORA2BALDH1A1MEN1
SCHEMBL23041392 0.73 DGKA (0.40) GAAKDM4EALDH1A1MEN1KMT2A
SCHEMBL19420291 0.72 ALDH1A1 (0.38) GAAHTTKDM4EALDH1A1PLA2G4A
SCHEMBL19420290 0.72 ALDH1A1 (0.35) GAAKDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011236175-A N-METHYL ISOCYANURATE COMPOUND SHIKOKU CHEM CORP 2011-11-24 JP disclosed