Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27408901 | 0.88 | KMT2A (0.49) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL27325273 | 0.88 | KMT2A (0.54) | HIF1ARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL27315061 | 0.86 | CYP1A2 (0.49) | RAB9ANPC1SMN1; SMN2POLBP4HTM | |
| SCHEMBL27309740 | 0.86 | KMT2A (0.50) | HIF1ARAB9ANPC1TP53ALDH1A1 | |
| SCHEMBL9429244 | 0.84 | NPC1 (0.56) | HIF1ARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL6175924 | 0.81 | CA1 (0.50) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL27319189 | 0.80 | GFER (0.49) | HIF1ASMN1; SMN2TP53RECQLGAA | |
| SCHEMBL27322188 | 0.77 | PTGS2 (0.59) | SMN1; SMN2TP53ALOX15ALDH1A1RECQL | |
| SCHEMBL27311725 | 0.76 | ALDH1A1 (0.48) | TP53ALDH1A1MAPTGAALMNA | |
| SCHEMBL27315064 | 0.76 | ALDH1A1 (0.50) | TP53ALOX15ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051074-C | Isoxazole-4-carboxamides and hydroxyalkylidenecyanoacetamides pharmaceuticals containing these compounds and their use | HOECHST AG (DE) | 2000-04-05 | — | — | CN | disclosed |
| CN-1056684-A | Different azoles-4-carboxylic acid amides and hydroxy alkylidene Malonamide nitrile contains the medicine of these compounds and their application | HOECHST AG (DE) | 1991-12-04 | — | — | CN | disclosed |