Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27325273 | 0.92 | KMT2A (0.54) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27309740 | 0.90 | KMT2A (0.50) | KMT2ATDP1RAB9ANPC1ALDH1A1 | |
| SCHEMBL27315061 | 0.90 | CYP1A2 (0.49) | KMT2ARAB9ANPC1SMN1; SMN2P4HTM | |
| SCHEMBL27323098 | 0.88 | HIF1A (0.53) | KMT2ATDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27319189 | 0.84 | GFER (0.49) | KMT2ASMN1; SMN2TP53CA12CA2 | |
| SCHEMBL27322188 | 0.81 | PTGS2 (0.59) | KMT2ASMN1; SMN2ALDH1A1TP53HSD17B10 | |
| SCHEMBL28148161 | 0.80 | NPC1 (0.56) | RAB9ANPC1SMN1; SMN2TP53NPSR1 | |
| SCHEMBL27311725 | 0.80 | ALDH1A1 (0.48) | KMT2AALDH1A1TP53KDM4EMAPT | |
| SCHEMBL27315064 | 0.80 | ALDH1A1 (0.50) | KMT2ATDP1ALDH1A1TP53KDM4E | |
| SCHEMBL27622444 | 0.79 | SRD5A2 (0.52) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051074-C | Isoxazole-4-carboxamides and hydroxyalkylidenecyanoacetamides pharmaceuticals containing these compounds and their use | HOECHST AG (DE) | 2000-04-05 | — | — | CN | disclosed |
| CN-1056684-A | Different azoles-4-carboxylic acid amides and hydroxy alkylidene Malonamide nitrile contains the medicine of these compounds and their application | HOECHST AG (DE) | 1991-12-04 | — | — | CN | disclosed |