Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27319189 | 0.84 | GFER (0.49) | LMNAGAAKMT2ATP53GFER | |
| SCHEMBL27322188 | 0.81 | PTGS2 (0.59) | ALDH1A1LMNAGAAKMT2ATP53 | |
| SCHEMBL28148161 | 0.80 | NPC1 (0.56) | LMNATP53MAPTTHRBGFER | |
| SCHEMBL27325273 | 0.80 | KMT2A (0.54) | ALDH1A1L3MBTL1LMNAGAAKMT2A | |
| SCHEMBL27315064 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4EKMT2ATP53 | |
| SCHEMBL27408901 | 0.80 | KMT2A (0.49) | ALDH1A1KDM4EKMT2ATP53MAPT | |
| SCHEMBL27309740 | 0.78 | KMT2A (0.50) | ALDH1A1KDM4EKMT2ATP53MAPT | |
| SCHEMBL27315061 | 0.78 | CYP1A2 (0.49) | KMT2AGFER | |
| SCHEMBL27318293 | 0.76 | AKR1C3 (0.58) | ALDH1A1LMNATSHRKDM4EKMT2A | |
| SCHEMBL27318291 | 0.76 | PKM (0.52) | ALDH1A1LMNATSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051074-C | Isoxazole-4-carboxamides and hydroxyalkylidenecyanoacetamides pharmaceuticals containing these compounds and their use | HOECHST AG (DE) | 2000-04-05 | — | — | CN | claimed |
| CN-1056684-A | Different azoles-4-carboxylic acid amides and hydroxy alkylidene Malonamide nitrile contains the medicine of these compounds and their application | HOECHST AG (DE) | 1991-12-04 | — | — | CN | claimed |
| CN-1051074-C | Isoxazole-4-carboxamides and hydroxyalkylidenecyanoacetamides pharmaceuticals containing these compounds and their use | HOECHST AG (DE) | 2000-04-05 | — | — | CN | disclosed |
| CN-1056684-A | Different azoles-4-carboxylic acid amides and hydroxy alkylidene Malonamide nitrile contains the medicine of these compounds and their application | HOECHST AG (DE) | 1991-12-04 | — | — | CN | disclosed |