Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908528 | 0.87 | MMP8 (0.64) | MMP8MEN1NPC1KMT2ACA12 | |
| SCHEMBL8200333 | 0.85 | MMP8 (0.55) | MMP8MEN1NPC1KMT2ACA12 | |
| SCHEMBL27354703 | 0.85 | MMP8 (0.49) | MMP8MEN1NPC1KMT2ACA12 | |
| SCHEMBL27620198 | 0.83 | CA2 (0.41) | MMP8CA12CA1CA2CA9 | |
| SCHEMBL7093633 | 0.83 | MMP8 (0.52) | MMP8MEN1NPC1KMT2ACA12 | |
| SCHEMBL7093345 | 0.82 | NPC1 (0.56) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL7095774 | 0.81 | MMP8 (0.50) | MMP8MEN1NPC1KMT2ACA12 | |
| SCHEMBL7092555 | 0.80 | MMP8 (0.59) | MMP8MEN1NPC1KMT2ACA12 | |
| SCHEMBL27676660 | 0.78 | MMP8 (0.54) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL7925167 | 0.78 | MMP8 (0.47) | MMP8MEN1NPC1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051311-C | N-heteroaryl-n'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 2000-04-12 | — | — | CN | disclosed |
| CN-1100417-A | N-heteroaryl-n'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 1995-03-22 | — | — | CN | disclosed |