SCHEMBL27344634

SCHEMBL27344634

CCCc1nc(C(O)CCC)c(C(N)=O)[nH]1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27319990 0.92 GPR84 (0.35)
SCHEMBL27344640 0.81 GPR84 (0.35)
SCHEMBL27431049 0.77 GPR84 (0.36)
SCHEMBL11086405 0.76 GLA (0.32) GLAPOLB
SCHEMBL4846607 0.76 KDM5B (0.33) GLAPOLB
SCHEMBL30296121 0.74 POLB (0.38) GLAPOLB
SCHEMBL5990880 0.74 MAPK1 (0.39) GLAPOLB
SCHEMBL7234563 0.74 ALDH1A1 (0.39) GLAPOLB
SCHEMBL27323698 0.73 ALDH1A1 (0.44) GLA
SCHEMBL27334880 0.71 ALDH1A1 (0.35) GLAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1121859-C Process for preparing pharmaceutical composition for treatment or prevention hypertension SNAKYO CO LTD (JP) 2003-09-24 CN disclosed
CN-1101384-C Process for preparing 1-biphenylmethylimidazole derivatives SANKYO CO (JP) 2003-02-12 CN disclosed
CN-1045770-C Process for preparing 1-biphenylmethylimidazole derivatives SANKYO CO (JP) 1999-10-20 CN disclosed
CN-1189490-A Process for preparing 1-biphenylmethylimidazole derivatives SANKYO CO (JP) 1998-08-05 CN disclosed
CN-1188645-A Process for preparing pharmaceutical composition for treatment or prevention hypertension SNAKYO CO LTD (JP) 1998-07-29 CN disclosed