Sugi Predict

Sugi Predict / Compounds / SCHEMBL273511

SCHEMBL273511

SCHEMBL273511

CC(C)COc1ccc(Cl)cc1C=O

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 1/20 0.50
▸ PTGER1 P34995 8/20 0.47
▸ ALDH1A1 P00352 3/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ PKM P14618 1/20 0.47
▸ HPGD P15428 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ ERN1 O75460 1/20 0.43
▸ GAA P10253 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ MAPT P10636 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ GPR55 Q9Y2T6 1/20 0.40
▸ S1PR4 O95977 1/20 0.40
▸ TBXA2R P21731 1/20 0.40
▸ PPARG P37231 1/20 0.40
▸ PTGER3 P43115 1/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14784711 0.88 HPGD (0.46) KDM1APTGER1ALDH1A1KDM4EPKM
SCHEMBL14785195 0.85 ALDH1A1 (0.44) PTGER1ALDH1A1KDM4EPKMHPGD
SCHEMBL27847667 0.85 ALDH1A1 (0.44) KDM1APTGER1ALDH1A1KDM4EPKM
SCHEMBL14785103 0.85 ALDH1A1 (0.44) KDM1APTGER1ALDH1A1KDM4EPKM
SCHEMBL15051905 0.84 HPGD (0.46) ALDH1A1KDM4EPKMHPGDTSHR
SCHEMBL2562900 0.83 GAA (0.47) PTGER1ALDH1A1KDM4EPKMHPGD
SCHEMBL25327365 0.82 FDPS (0.50) ALDH1A1HPGDTSHRGAATDP1
SCHEMBL120322 0.82 HPGD (0.47) ALDH1A1KDM4EPKMHPGDTSHR
SCHEMBL1185190 0.81 HPGD (0.64) ALDH1A1KDM4EPKMHPGDTSHR
SCHEMBL30902394 0.81 HPGD (0.64) ALDH1A1KDM4EPKMHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619097-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2025-09-24 — — EP disclosed
WO-2025106477-A1 NOVEL AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2025-05-22 — — WO disclosed
WO-2024107434-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2024-05-23 — — WO disclosed
EP-2766344-B1 EP1 RECEPTOR LIGANDS ESTEVE LABOR DR (ES) 2017-05-03 — — EP disclosed
US-8133898-B2 Renin inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-03-13 — — US disclosed
US-20100137310-A1 RENIN INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-06-03 — — US disclosed
US-20100120669-A1 THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE BOUILLOT ANNE MARIE JEANNE 2010-05-13 — — US disclosed
EP-2125799-A1 THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE Smithkline Beecham Corporation (US) 2009-12-02 — — EP disclosed
US-20090239845-A1 PYRAZOLE COMPOUNDS AS PROSTAGLANDIN RECEPTORS LIGANDS CONWAY ELIZABETH ANN 2009-09-24 — — US disclosed
WO-2008121506-A2 RENIN INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-10-09 — — WO disclosed
WO-2008104524-A1 THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE SMITHKLINE BEECHAM CORPORATION (US) 2008-09-04 — — WO disclosed
US-20080207708-A1 Oxazole and Thiazole Compounds and Their Use in the Treatment of Pge2 Mediated Disorders GLAXO GROUP LIMITED (GB) 2008-08-28 — — US disclosed
EP-1874776-A1 OXAZOLE AND THIAZOLE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PGE2 MEDIATED DISORDERS GLAXO GROUP LIMITED (GB) 2008-01-09 — — EP disclosed
EP-1874303-A1 PYRAZOLE COMPOUNDS AS PROSTAGLANDIN RECEPTORS LIGANDS GLAXO GROUP LIMITED (GB) 2008-01-09 — — EP disclosed
US-20070072906-A1 Pyrrole compounds GLAXO GROUP LIMITED (GB) 2007-03-29 — — US disclosed
US-20070072906-A1 Pyrrole compounds GLAXO GROUP LIMITED (GB) 2007-03-29 — — US disclosed
US-20070072906-A1 Pyrrole compounds GLAXO GROUP LIMITED (GB) 2007-03-29 — — US disclosed
WO-2006114313-A1 PYRAZOLE COMPOUNDS AS PROSTAGLANDIN RECEPTORS LIGANDS GLAXO GROUP LIMITED (GB) 2006-11-02 — — WO disclosed
WO-2006114274-A1 OXAZOLE AND THIAZOLE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PGE2 MEDIATED DISORDERS GLAXO GROUP LIMITED (GB) 2006-11-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239845-A1 PYRAZOLE COMPOUNDS AS PROSTAGLANDIN RECEPTORS LIGANDS PTGER1, PTGDR, PTGIR KDM1A 3230/4885PTGER1 1/4885ALDH1A1 1438/4885
US-20080207708-A1 Oxazole and Thiazole Compounds and Their Use in the Treatment of Pge2 Mediated Disorders PTGER1, PTGER2, PTGER4 KDM1A 2963/4885PTGER1 1/4885ALDH1A1 647/4885
US-20070072906-A1 Pyrrole compounds PRMT9, EPOR, ADCYAP1R1 KDM1A 1580/4885PTGER1 224/4885ALDH1A1 2436/4885
US-20100137310-A1 RENIN INHIBITORS REN, ACE, PRSS3 KDM1A 2916/4885PTGER1 975/4885ALDH1A1 1131/4885
US-20100120669-A1 THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE SCD, SCD5, FADS2 KDM1A 1174/4885PTGER1 923/4885ALDH1A1 458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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