Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | FABP3 | P05413 | 5/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8951891 | 0.96 | FFAR3 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL446877 | 0.87 | TSHR (0.41) | TSHR | |
| SCHEMBL848574 | 0.78 | PHF8 (0.45) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28047872 | 0.78 | TSHR (0.59) | TSHR | |
| SCHEMBL28049493 | 0.77 | TSHR (0.33) | TSHR | |
| SCHEMBL5690184 | 0.77 | TSHR (0.33) | TSHR | |
| SCHEMBL28236422 | 0.76 | SQLE (0.31) | TSHR | |
| SCHEMBL28296514 | 0.76 | ALDH1A1 (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27574835 | 0.75 | TSHR (0.32) | TSHR | |
| SCHEMBL28488361 | 0.71 | FFAR3 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1285713-C | Method for preparing polyisobutylene base oil soluble organic molybdenum lubricating additives | UNIV SHANGHAI (CN) | 2006-11-22 | — | — | CN | claimed |
| CN-1632084-A | Method for preparing polyisobutylene base oil soluble organic molybdenum lubricating additives | UNIV SHANGHAI (CN) | 2005-06-29 | — | — | CN | claimed |
| CN-1285713-C | Method for preparing polyisobutylene base oil soluble organic molybdenum lubricating additives | UNIV SHANGHAI (CN) | 2006-11-22 | — | — | CN | disclosed |
| CN-1632084-A | Method for preparing polyisobutylene base oil soluble organic molybdenum lubricating additives | UNIV SHANGHAI (CN) | 2005-06-29 | — | — | CN | disclosed |
| CN-1062752-A | GASOLINE COMPOSITION | SHELL INT RESEARCH (NL) | 1992-07-15 | — | — | CN | disclosed |