Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700259 | 0.88 | L3MBTL1 (0.46) | HSD11B1F2F10CA1CA2 | |
| SCHEMBL27334381 | 0.86 | MAPT (0.44) | HSD11B1CA12CA1CA2CA9 | |
| SCHEMBL8705533 | 0.77 | AOC2 (0.51) | TDP1MAPTL3MBTL1ALDH1A1POLB | |
| SCHEMBL8704323 | 0.75 | EGFR (0.40) | ERCC5FEN1PRSS1PRSS2PRSS3 | |
| SCHEMBL8699108 | 0.74 | SERPINE1 (0.39) | F2CA12CA1CA2CA9 | |
| SCHEMBL8705507 | 0.74 | PTGS1 (0.36) | F2F10ERCC5FEN1PRSS1 | |
| SCHEMBL27380654 | 0.73 | HSD17B1 (0.39) | HSD11B1F10PRSS1 | |
| SCHEMBL27383233 | 0.73 | F10 (0.34) | HSD11B1F2F10CA12CA1 | |
| SCHEMBL27379215 | 0.73 | ERCC5 (0.34) | F2F10CA12CA1CA2 | |
| SCHEMBL27364898 | 0.73 | F10 (0.32) | HSD11B1F2F10ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070173-C | Benzoylguanidine derivatives as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-08-29 | — | — | CN | disclosed |
| CN-1158606-A | Benzoylguanidine derivatives as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-09-03 | — | — | CN | disclosed |