Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | ITGA1 | P56199 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27334381 | 0.88 | MAPT (0.44) | L3MBTL1TDP1CA1CA2HSD11B1 | |
| SCHEMBL27360533 | 0.88 | HSD11B1 (0.38) | L3MBTL1TDP1CA1CA2HSD11B1 | |
| SCHEMBL8705533 | 0.79 | AOC2 (0.51) | L3MBTL1TDP1 | |
| SCHEMBL8704323 | 0.77 | EGFR (0.40) | — | |
| SCHEMBL8699108 | 0.76 | SERPINE1 (0.39) | CA1CA2F2CA9 | |
| SCHEMBL8705507 | 0.76 | PTGS1 (0.36) | F2F10 | |
| SCHEMBL27501518 | 0.76 | ASH1L (0.52) | — | |
| SCHEMBL27379215 | 0.75 | ERCC5 (0.34) | CA1CA2F2F10CA9 | |
| SCHEMBL27380654 | 0.75 | HSD17B1 (0.39) | HSD11B1F10 | |
| SCHEMBL27383233 | 0.75 | F10 (0.34) | CA1CA2HSD11B1F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |