Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | FURIN | P09958 | 8/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22695691 | 0.83 | SIRT6 (0.46) | SIRT6SIRT1FURINPRSS1NMT2 | |
| SCHEMBL20235809 | 0.81 | FURIN (0.47) | SIRT6SIRT1FURINPRSS1NMT2 | |
| SCHEMBL26496635 | 0.80 | NMT1 (0.46) | SIRT6SIRT1FURINPRSS1NMT2 | |
| SCHEMBL22788858 | 0.78 | ALDH1A1 (0.34) | — | |
| SCHEMBL24642654 | 0.77 | SIRT6 (0.46) | SIRT6SIRT1FURINPRSS1NMT2 | |
| SCHEMBL23105876 | 0.76 | SIRT6 (0.39) | SIRT6SIRT1FURINNMT2NMT1 | |
| SCHEMBL21437110 | 0.76 | NMT2 (0.45) | SIRT6SIRT1FURINPRSS1NMT2 | |
| SCHEMBL8355213 | 0.76 | NMT2 (0.45) | SIRT6SIRT1FURINPRSS1NMT2 | |
| SCHEMBL24642332 | 0.75 | NMT1 (0.46) | SIRT6SIRT1FURINPRSS1NMT2 | |
| SCHEMBL24642309 | 0.74 | GLO1 (0.37) | FURINPRSS1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015229-A1 | PROTEASE/ENZYME CLEAVABLE LINKER-PAYLOADS AND PROTEIN CONJUGATES | SUTRO BIOPHARMA, INC. (US) | 2024-01-18 | — | — | WO | disclosed |