Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882102 | 0.85 | HTT (0.55) | CHRNB2CHRNA7CHRNA4BCHEHTT | |
| SCHEMBL19734471 | 0.84 | CHRNB2 (0.55) | CHRNB2CHRNA7CHRNA4HTTCYP3A4 | |
| Water SCHEMBL11540986 | 0.83 | HTT (0.53) | CHRNB2CHRNA7CHRNA4BCHEHTT | |
| SCHEMBL19734470 | 0.83 | CHRNB2 (0.54) | CHRNB2CHRNA7CHRNA4CYP3A4MAPT | |
| SCHEMBL14193990 | 0.82 | CHRNB2 (0.64) | CHRNB2CHRNA7CHRNA4BCHEHTT | |
| SCHEMBL8250436 | 0.80 | ALDH1A1 (0.47) | CHRNB2CHRNA7CHRNA4HTTCYP3A4 | |
| SCHEMBL21790486 | 0.79 | CHRNB2 (0.53) | CHRNB2CHRNA7CHRNA4BCHEHTT | |
| SCHEMBL3886866 | 0.79 | HTR6 (0.63) | CHRNB2CHRNA7CHRNA4BCHEHTT | |
| SCHEMBL22132140 | 0.79 | CHRNB2 (0.47) | CHRNB2CHRNA7CHRNA4BCHEHTT | |
| SCHEMBL5459223 | 0.79 | ALDH1A1 (0.50) | CHRNB2CHRNA7CHRNA4BCHEHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024039858-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |