Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27381422 | 0.89 | LTA4H (0.39) | POLBNPC1ALDH1A1KMT2AKDM4E | |
| SCHEMBL27355461 | 0.87 | F2 (0.38) | NPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL27363422 | 0.85 | KMT2A (0.44) | POLBNPC1KMT2AMEN1MAPT | |
| SCHEMBL27383640 | 0.85 | ALDH1A1 (0.41) | POLBNPC1ALDH1A1KMT2AKDM4E | |
| SCHEMBL27357166 | 0.83 | ATM (0.44) | NPC1ALDH1A1KMT2AKDM4ETSHR | |
| SCHEMBL27362428 | 0.76 | PKM (0.35) | NPC1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL27364669 | 0.74 | NPC1 (0.34) | NPC1ALDH1A1KMT2AKDM4ETSHR | |
| SCHEMBL27362385 | 0.73 | TAAR1 (0.37) | NPC1ALDH1A1KDM4EHDAC8 | |
| SCHEMBL6807033 | 0.70 | CTRB1 (0.50) | CTRB1POLBGLSNPC1ALDH1A1 | |
| SCHEMBL6498375 | 0.70 | CTRB1 (0.68) | CTRB1GLSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070480-C | 2-amino-benzoxanones for the treatment of viral infections | SEARLE & CO (US) | 2001-09-05 | — | — | CN | disclosed |