Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27363422 | 0.85 | KMT2A (0.44) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL27355463 | 0.83 | CTRB1 (0.38) | NPC1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL27383640 | 0.81 | ALDH1A1 (0.41) | SMN1; SMN2RAB9ANPC1GAAALDH1A1 | |
| SCHEMBL27381422 | 0.80 | LTA4H (0.39) | SMN1; SMN2RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL27362428 | 0.76 | PKM (0.35) | SMN1; SMN2RAB9ANPC1L3MBTL1GAA | |
| SCHEMBL27364669 | 0.74 | NPC1 (0.34) | ATMSMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL27355461 | 0.74 | F2 (0.38) | SMN1; SMN2RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL27362385 | 0.73 | TAAR1 (0.37) | ATMSMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL6496069 | 0.70 | ELANE (0.50) | ATMSMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL27357170 | 0.67 | HDAC6 (0.38) | ATMRAB9ANPC1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070480-C | 2-amino-benzoxanones for the treatment of viral infections | SEARLE & CO (US) | 2001-09-05 | — | — | CN | disclosed |