Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27357166 | 0.85 | ATM (0.44) | KMT2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL27355463 | 0.85 | CTRB1 (0.38) | KMT2ANPC1MEN1MAPTPOLB | |
| SCHEMBL27383640 | 0.84 | ALDH1A1 (0.41) | KMT2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL27381422 | 0.82 | LTA4H (0.39) | KMT2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL27362428 | 0.79 | PKM (0.35) | KMT2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL27355461 | 0.78 | F2 (0.38) | KMT2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL27364669 | 0.77 | NPC1 (0.34) | KMT2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL27362385 | 0.75 | TAAR1 (0.37) | RAB9ANPC1SMN1; SMN2MMP3 | |
| SCHEMBL27357170 | 0.69 | HDAC6 (0.38) | KMT2ARAB9ANPC1ROCK2MEN1 | |
| SCHEMBL6506565 | 0.68 | ELANE (0.53) | KMT2ATRPV1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070480-C | 2-amino-benzoxanones for the treatment of viral infections | SEARLE & CO (US) | 2001-09-05 | — | — | CN | claimed |
| CN-1070480-C | 2-amino-benzoxanones for the treatment of viral infections | SEARLE & CO (US) | 2001-09-05 | — | — | CN | disclosed |