Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 2/20 | 0.42 |
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1188671 | 0.81 | RAPGEF4 (0.53) | — | |
| SCHEMBL7533413 | 0.81 | TSHR (0.42) | HTR6TSHR | |
| SCHEMBL27359857 | 0.79 | HRH3 (0.44) | LOXL2 | |
| SCHEMBL630874 | 0.79 | MEN1 (0.42) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9782318 | 0.78 | HTR6 (0.47) | HTR6PNMTENPP2LOXL2DDB1 | |
| SCHEMBL10388288 | 0.78 | SIGMAR1 (0.47) | HTR6 | |
| SCHEMBL27903338 | 0.77 | HTR6 (0.53) | HTR6PNMTENPP2LOXL2DDB1 | |
| SCHEMBL22417128 | 0.75 | HTR6 (0.51) | HTR6PNMTENPP2LOXL2DDB1 | |
| SCHEMBL7351050 | 0.75 | HDAC4 (0.44) | HTR6 | |
| SCHEMBL5543430 | 0.74 | LPL (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368064-A | 1,2, 3-triazole derivative and insecticide and acaricide comprising the same as active ingredient | 北兴化学工业株式会社 | 2018-08-03 | — | — | CN | disclosed |
| CN-102612416-A | Silver-(conjugated compound) complex | SUMITOMO CHEMICAL CO | 2012-07-25 | — | — | CN | disclosed |
| CN-1069272-A | The method for preparing benzo pyrrole or thiapyran and pyrazoles | BOOTS CO PLC (GB) | 1993-02-24 | — | — | CN | disclosed |