Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1172183 | 0.85 | CYP1A2 (0.54) | MEN1KMT2AMAPTALDH1A1KCNK3 | |
| SCHEMBL5476577 | 0.84 | CYP3A4 (0.52) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL2096799 | 0.84 | SIGMAR1 (0.40) | — | |
| SCHEMBL2089828 | 0.84 | RAPGEF4 (0.47) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL515009 | 0.84 | DDX3X (0.53) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL1189638 | 0.84 | MEN1 (0.50) | MEN1KMT2AGAARAB9A | |
| SCHEMBL57436 | 0.84 | MEN1 (0.53) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL7482595 | 0.82 | MGLL (0.55) | POLB | |
| SCHEMBL8390036 | 0.82 | KEAP1 (0.53) | ALDH1A1HTTPOLBRAB9A | |
| SCHEMBL7709618 | 0.80 | ALDH1A1 (0.45) | ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2420521-B1 | Composite of a polyaddition polymer | BRECKLE CHEMICALS & TECHNICS GMBH (DE) | 2013-10-23 | — | — | EP | disclosed |
| EP-2420521-A1 | Composite of a polyaddition polymer | Sembella Gmbh (AT) | 2012-02-22 | — | — | EP | disclosed |