Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALPG | P10696 | 2/20 | 0.39 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185568 | 0.80 | KMT2A (0.43) | LMNAKMT2ATSHRF2L3MBTL1 | |
| SCHEMBL28048388 | 0.74 | ALPG (0.36) | TSHRALPGPLAAALPLFDPS | |
| SCHEMBL10554675 | 0.73 | TNK2 (0.41) | KMT2ATSHRCYP1A2CYP2C19CYP2D6 | |
| Benzoic Acid SCHEMBL2518954 | 0.73 | KMT2A (0.50) | KMT2ATSHRALPGPLAAALPL | |
| SCHEMBL6259211 | 0.71 | ALDH1A1 (0.40) | LMNAKMT2AHTT | |
| SCHEMBL9880601 | 0.70 | ALDH1A1 (0.46) | KMT2ATSHRL3MBTL1TDP1MAPK1 | |
| SCHEMBL27464997 | 0.68 | TSHR (0.47) | LMNAKMT2ATSHRF2CYP2C19 | |
| SCHEMBL2804720 | 0.68 | KMT2A (0.52) | LMNAKMT2ATSHRF2CYP2D6 | |
| SCHEMBL13604014 | 0.66 | LMNA (0.47) | LMNAKMT2ATSHRF2TDP1 | |
| SCHEMBL27635032 | 0.66 | LMNA (0.47) | LMNAKMT2ATSHRF2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1064042-C | Intermediate of benzazepine derivative | YAMANOUCHI PHARMA CO LTD (JP) | 2001-04-04 | — | — | CN | disclosed |
| CN-1040748-C | Benzazepine derivatives, pharmaceutical compositions and intermediates thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1998-11-18 | — | — | CN | disclosed |
| CN-1198437-A | Intermediate of benzazepine derivative | YAMANOUCHI PHARMA CO LTD (JP) | 1998-11-11 | — | — | CN | disclosed |
| CN-1129934-A | Benzazepine derivatives, pharmaceutical compositions and intermediates thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1996-08-28 | — | — | CN | disclosed |