Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28386445 | 0.79 | CHRNB2 (0.40) | KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL1682004 | 0.75 | CHRNB2 (0.40) | KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6673530 | 0.74 | CHRNB2 (0.39) | KMT2ALMNATSHRMAPTSMN1; SMN2 | |
| SCHEMBL1045991 | 0.71 | SMN1; SMN2 (0.58) | KMT2ALMNATSHRMAPTCYP2D6 | |
| SCHEMBL16991360 | 0.70 | CHRNB2 (0.40) | KMT2AMAPTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL2285950 | 0.70 | KMT2A (0.39) | KMT2ATSHRSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL31527863 | 0.70 | CA1 (0.49) | KMT2ALMNASMN1; SMN2 | |
| SCHEMBL2262194 | 0.70 | LMNA (0.56) | KMT2ASLC6A3LMNAMETAP2METAP1 | |
| SCHEMBL30320367 | 0.69 | KMT2A (0.54) | KMT2AGRM5LMNATSHRMAPT | |
| SCHEMBL14369862 | 0.69 | NPC1 (0.55) | KMT2AGRM5LMNAHDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116448893-A | Characterization method of cellulose molecular weight | 中国科学院化学研究所 | 2023-07-18 | — | — | CN | claimed |
| US-20100239673-A1 | Blood compatible nanomaterials and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-09-23 | — | — | US | claimed |
| WO-2008045021-A2 | BLOOD COMPATIBLE NANOMATERIALS AND METHODS OF MAKING AND USING THE SAME | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2008-04-17 | — | — | WO | claimed |
| CN-117561262-A | Macrocyclic TAK1 inhibitors | 阿奎利恩有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-116448893-A | Characterization method of cellulose molecular weight | 中国科学院化学研究所 | 2023-07-18 | — | — | CN | disclosed |
| CN-116448893-A | Characterization method of cellulose molecular weight | 中国科学院化学研究所 | 2023-07-18 | — | — | CN | disclosed |
| US-20100239673-A1 | Blood compatible nanomaterials and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-09-23 | — | — | US | disclosed |
| WO-2008045021-A2 | BLOOD COMPATIBLE NANOMATERIALS AND METHODS OF MAKING AND USING THE SAME | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100239673-A1 | Blood compatible nanomaterials and methods of making and using the same | MB, ICAM1, F3 | KMT2A 2587/4885GRM5 4569/4885SLC6A3 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.