2-Pyrrolidone

2-Pyrrolidone

SCHEMBL27365042

C=COC(=O)C(=C)C.O=C1CCCN1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.47
CRBN Q96SW2 2/20 0.41
FKBP5 Q13451 1/20 0.41
KDM4E B2RXH2 2/20 0.32
GAA P10253 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL10417979 0.89 OR51E2 (0.38) OR51E2CRBNFKBP5
2-Pyrrolidone SCHEMBL22534 0.85 OR51E2 (0.52) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL4595907 0.85 OR51E2 (0.52) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL28565455 0.84 OR51E2 (0.50) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL933908 0.84 OR51E2 (0.50) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL7090022 0.82 ALDH1A1 (0.52) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL28270057 0.82 OR51E2 (0.44) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27876042 0.81 OR51E2 (0.47) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL28279632 0.79 OR51E2 (0.48) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL8965954 0.79 OR51E2 (0.48) OR51E2CRBNFKBP5KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1057327-C Cleaning composition PROCTER & GAMBLE (US) 2000-10-11 CN disclosed
CN-1120851-A Cleansing compositions PROCTER & GAMBLE (US) 1996-04-17 CN disclosed
CN-1116858-A Cleaning composition PROCTER & GAMBLE (US) 1996-02-14 CN disclosed