SCHEMBL27367131

SCHEMBL27367131

CC(C)N(C)C(=O)Cc1cccc2ccc(F)cc12

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 1/20 0.40
SIGMAR1 Q99720 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KMT2A Q03164 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
PTGDR2 Q9Y5Y4 4/20 0.38
MTNR1A P48039 2/20 0.38
MTNR1B P49286 1/20 0.38
MEN1 O00255 2/20 0.37
NQO2 P16083 1/20 0.37
LMNA P02545 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31618186 0.90 SIGMAR1 (0.39) PIN1SIGMAR1L3MBTL1KMT2ATDP1
SCHEMBL27367115 0.83 HCRTR1 (0.41) PIN1SIGMAR1KMT2ATDP1PTGDR2
SCHEMBL27367147 0.81 SIGMAR1 (0.48) SIGMAR1KMT2APTGDR2MTNR1AMTNR1B
SCHEMBL5235807 0.79 TDP1 (0.45) PIN1L3MBTL1KMT2ATDP1PTGDR2
SCHEMBL24821196 0.77 TDP1 (0.64) PIN1KMT2ATDP1PTGDR2MTNR1A
SCHEMBL27367110 0.76 HPGD (0.56) L3MBTL1KMT2ATDP1MEN1LMNA
SCHEMBL31618222 0.75 SIGMAR1 (0.42) PIN1SIGMAR1L3MBTL1KMT2ATDP1
SCHEMBL31618139 0.75 SIGMAR1 (0.42) PIN1SIGMAR1L3MBTL1KMT2ATDP1
SCHEMBL27366186 0.74 HTR2A (0.52) MTNR1AMTNR1BNQO2
Fumaric Acid SCHEMBL31331788 0.73 HTR2A (0.46) KMT2AMTNR1AMTNR1BMEN1NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 PIN1 745/4885SIGMAR1 623/4885L3MBTL1 2935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.