SCHEMBL27367115

SCHEMBL27367115

CCN(C)C(=O)Cc1cccc2ccc(F)cc12

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 1/20 0.41
MTNR1A P48039 2/20 0.41
MTNR1B P49286 1/20 0.41
POLB P06746 2/20 0.40
SIGMAR1 Q99720 1/20 0.40
RIPK1 Q13546 2/20 0.39
KMT2A Q03164 6/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PIN1 Q13526 1/20 0.38
MEN1 O00255 5/20 0.38
HTR2A P28223 1/20 0.38
TSHR P16473 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31618099 0.89 HCRTR1 (0.41) HCRTR1POLBSIGMAR1RIPK1KMT2A
SCHEMBL27367131 0.83 PIN1 (0.40) MTNR1AMTNR1BSIGMAR1KMT2APTGDR2
SCHEMBL27367147 0.82 SIGMAR1 (0.48) MTNR1AMTNR1BSIGMAR1KMT2APTGDR2
SCHEMBL5235807 0.80 TDP1 (0.45) MTNR1AMTNR1BKMT2APTGDR2TDP1
SCHEMBL27367110 0.80 HPGD (0.56) POLBKMT2ATDP1MEN1HPGD
SCHEMBL24821196 0.78 TDP1 (0.64) MTNR1AMTNR1BKMT2APTGDR2TDP1
SCHEMBL31618139 0.76 SIGMAR1 (0.42) HCRTR1POLBSIGMAR1KMT2ATDP1
SCHEMBL31618222 0.76 SIGMAR1 (0.42) HCRTR1POLBSIGMAR1KMT2ATDP1
SCHEMBL3276262 0.74 KMT2A (0.44) POLBKMT2APTGDR2MEN1
SCHEMBL27366184 0.73 HTR2A (0.67) MTNR1AMTNR1BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 HCRTR1 298/4885MTNR1A 1247/4885MTNR1B 757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.