SCHEMBL27367147

SCHEMBL27367147

CN(C(=O)Cc1cccc2ccc(F)cc12)C1CC1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.48
DPP4 P27487 3/20 0.45
DPP9 Q86TI2 2/20 0.45
CHRM1 P11229 1/20 0.44
CCR5 P51681 3/20 0.43
PTGDR2 Q9Y5Y4 4/20 0.42
KMT2A Q03164 1/20 0.42
OPRK1 P41145 1/20 0.40
DPP8 Q6V1X1 1/20 0.40
DPP7 Q9UHL4 1/20 0.40
CCR3 P51677 1/20 0.39
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27529191 0.86 SIGMAR1 (0.47) SIGMAR1CHRM1CCR5KMT2AOPRK1
SCHEMBL27553023 0.86 SIGMAR1 (0.47) SIGMAR1CHRM1CCR5KMT2AOPRK1
SCHEMBL27366961 0.86 CHRM1 (0.54) SIGMAR1CHRM1CCR5KMT2AOPRK1
SCHEMBL27366400 0.84 MTNR1A (0.57) MTNR1AMTNR1B
SCHEMBL27367115 0.82 HCRTR1 (0.41) SIGMAR1PTGDR2KMT2AMTNR1AMTNR1B
SCHEMBL27367131 0.81 PIN1 (0.40) SIGMAR1PTGDR2KMT2AMTNR1AMTNR1B
SCHEMBL5235807 0.78 TDP1 (0.45) PTGDR2KMT2AMTNR1AMTNR1B
SCHEMBL27367140 0.76 HTR2A (0.54) CHRM1OPRK1MTNR1AMTNR1B
SCHEMBL24821196 0.76 TDP1 (0.64) PTGDR2KMT2AMTNR1AMTNR1B
SCHEMBL2410035 0.76 TSHR (0.61) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 SIGMAR1 623/4885DPP4 3962/4885DPP9 4328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.