SCHEMBL27367110

SCHEMBL27367110

CCOC(=O)Cc1cccc2ccc(F)cc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.56
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.56
POLB P06746 1/20 0.56
HTT P42858 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
ALDH1A1 P00352 5/20 0.48
L3MBTL1 Q9Y468 5/20 0.48
KDM4E B2RXH2 3/20 0.48
MAPT P10636 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
LMNA P02545 1/20 0.46
AHR P35869 1/20 0.46
PTGS2 P35354 2/20 0.45
PTGS1 P23219 1/20 0.45
GAA P10253 2/20 0.44
MAOB P27338 1/20 0.44
GLA P06280 1/20 0.44
PRNP P04156 1/20 0.44
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31618148 0.89 KMT2A (0.50) HPGDKMT2AMEN1POLBHTT
SCHEMBL15305557 0.86 L3MBTL1 (0.50) HPGDKMT2AMEN1POLBHTT
SCHEMBL15747695 0.84 KDM4E (0.55) HPGDKMT2AMEN1POLBHTT
SCHEMBL27366928 0.83 MAPT (0.48) HPGDKMT2AMEN1POLBHTT
SCHEMBL4752950 0.82 MTNR1A (0.59) HPGDALDH1A1L3MBTL1KDM4EMAPT
SCHEMBL29729685 0.82 KMT2A (0.62) HPGDKMT2AALDH1A1L3MBTL1KDM4E
SCHEMBL845701 0.82 KMT2A (0.62) HPGDKMT2AALDH1A1L3MBTL1KDM4E
SCHEMBL5235807 0.81 TDP1 (0.45) KMT2AMEN1L3MBTL1TDP1
SCHEMBL28332298 0.80 KMT2A (0.53) HPGDKMT2AMEN1POLBHTT
SCHEMBL27367115 0.80 HCRTR1 (0.41) HPGDKMT2AMEN1POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 HPGD 518/4885KMT2A 3007/4885MEN1 1154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.