Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 6/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22860677 | 0.79 | MCHR1 (0.38) | NPC1RAB9AMCHR1KMT2AFAAH | |
| SCHEMBL27366363 | 0.78 | FAAH (0.36) | NPC1RAB9AMCHR1FAAH | |
| SCHEMBL9218363 | 0.77 | FAAH (0.44) | KMT2AFAAHCA1CA2ACHE | |
| SCHEMBL5889332 | 0.77 | FAAH (0.44) | KMT2AFAAHCA1CA2ACHE | |
| SCHEMBL27367322 | 0.76 | CCKBR (0.35) | CCKBRNPC1RAB9AMCHR1LMNA | |
| SCHEMBL9215130 | 0.75 | CYP1A2 (0.41) | FAAH | |
| SCHEMBL13262741 | 0.74 | CA1 (0.48) | KMT2ACA1CA2ACHEEPHX2 | |
| SCHEMBL3195898 | 0.72 | GHSR (0.49) | KMT2AFAAHEPHX2 | |
| SCHEMBL20909776 | 0.72 | ACHE (0.44) | MCHR1FAAHCA1CA2ACHE | |
| SCHEMBL25554148 | 0.72 | MTNR1A (0.44) | KMT2AFAAHCA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |