Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367322 | 0.81 | CCKBR (0.35) | GPR119 | |
| SCHEMBL27367016 | 0.77 | ACHE (0.36) | ACHEDRD2DRD3 | |
| SCHEMBL27367345 | 0.66 | PDK1 (0.38) | — | |
| SCHEMBL27367100 | 0.65 | MCHR1 (0.38) | ACHEDRD2DRD3GPR119 | |
| SCHEMBL27367125 | 0.63 | MCHR1 (0.39) | ACHEDRD2DRD3 | |
| SCHEMBL27367215 | 0.62 | AOC3 (0.36) | ACHE | |
| SCHEMBL27367022 | 0.62 | HTR2C (0.45) | ACHE | |
| SCHEMBL6630069 | 0.61 | CYP2D6 (0.38) | — | |
| SCHEMBL20006885 | 0.61 | HTR1D (0.51) | DRD2DRD3 | |
| SCHEMBL13957550 | 0.61 | CYP2D6 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |