Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27247001 | 0.84 | MTNR1A (0.56) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27384259 | 0.84 | KMT2A (0.48) | RAB9AMAPK1NPC1MEN1KMT2A | |
| SCHEMBL27384644 | 0.83 | MAPK1 (0.46) | RAB9AMAPK1NPC1MEN1KMT2A | |
| SCHEMBL27384640 | 0.82 | MAPK1 (0.46) | RAB9AMAPK1NPC1MEN1KMT2A | |
| SCHEMBL27384339 | 0.79 | MAPK1 (0.42) | RAB9AMAPK1USP2NPC1MEN1 | |
| SCHEMBL27384649 | 0.78 | HTT (0.42) | RAB9AMAPK1NPC1MEN1KMT2A | |
| SCHEMBL27384505 | 0.78 | RAB9A (0.49) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27384652 | 0.77 | SMN1; SMN2 (0.41) | RAB9AMAPK1SMN1; SMN2HTT | |
| SCHEMBL27384854 | 0.75 | MAPK1 (0.41) | RAB9AMAPK1NPC1MEN1KMT2A | |
| SCHEMBL27384655 | 0.75 | EIF4A3 (0.48) | RAB9AMAPK1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |