Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27384644 | 0.97 | MAPK1 (0.46) | MAPK1EIF4A3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27384257 | 0.82 | RAB9A (0.50) | MAPK1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27384648 | 0.80 | EIF4A3 (0.48) | MAPK1EIF4A3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27382616 | 0.79 | EIF4A3 (0.51) | MAPK1EIF4A3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27384259 | 0.79 | KMT2A (0.48) | MAPK1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL27247001 | 0.79 | MTNR1A (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL27384339 | 0.78 | MAPK1 (0.42) | MAPK1EIF4A3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27383636 | 0.78 | EIF4A3 (0.47) | EIF4A3SMN1; SMN2RAB9ANPC1MTNR1A | |
| SCHEMBL27384655 | 0.77 | EIF4A3 (0.48) | MAPK1EIF4A3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27384011 | 0.77 | EIF4A3 (0.46) | MAPK1EIF4A3SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |