Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.37 |
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27400004 | 0.78 | IKBKB (0.35) | LIMK1IKBKBLCKBTKDYRK1A | |
| SCHEMBL27400870 | 0.78 | SYK (0.36) | LIMK1LCKBTKDYRK1ACDK9 | |
| SCHEMBL27398651 | 0.78 | LCK (0.37) | LIMK1IKBKBLMNALCKBTK | |
| SCHEMBL27399014 | 0.77 | LCK (0.51) | LIMK1IKBKBLMNALCKBTK | |
| SCHEMBL27399330 | 0.77 | DHODH (0.39) | LIMK1LMNALCKBTKPARP1 | |
| SCHEMBL27399603 | 0.76 | MKNK1 (0.40) | LIMK1IKBKBLMNALCKBTK | |
| SCHEMBL27398649 | 0.75 | MKNK1 (0.35) | IKBKBLMNALCKBTKMAPK1 | |
| SCHEMBL27400006 | 0.74 | DHODH (0.40) | LIMK1IKBKBLCKBTKCDK2 | |
| SCHEMBL27399247 | 0.74 | MKNK1 (0.50) | LIMK1IKBKBLMNALCKBTK | |
| SCHEMBL27399933 | 0.73 | PRMT5 (0.41) | LIMK1IKBKBLMNALCKBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |