SCHEMBL27404477

SCHEMBL27404477

CC(C)C(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(C)(C)CN

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 5/20 0.35
▸ REN P00797 1/20 0.35
▸ CTSD P07339 4/20 0.35
▸ CTSE P14091 4/20 0.35
▸ STAT3 P40763 7/20 0.34
▸ BACE1 P56817 2/20 0.34
▸ PREP P48147 1/20 0.33
▸ FAP Q12884 1/20 0.33
▸ ELANE P08246 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ PEPD P12955 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27317143 0.76 CTSD (0.38) ACERENCTSDCTSESTAT3
SCHEMBL27404606 0.74 CTSD (0.38) ACERENCTSDCTSESTAT3
SCHEMBL27404602 0.73 CTSD (0.41) ACERENCTSDCTSESTAT3
SCHEMBL27317324 0.73 CTSD (0.41) ACERENCTSDCTSESTAT3
SCHEMBL27410828 0.71 CTSD (0.39) ACERENCTSDCTSESTAT3
SCHEMBL17117574 0.69 PREP (0.46) ACERENPREPFAPLMNA
SCHEMBL30844309 0.69 GRB2 (0.54) CTSDCTSESTAT3BACE1PREP
SCHEMBL30721557 0.69 ACE (0.42) ACERENCTSDCTSESTAT3
SCHEMBL12766400 0.68 ACE (0.49) ACERENPREPFAPLMNA
SCHEMBL30563282 0.68 GRB2 (0.40) ACECTSDCTSESTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209028-A1 CNP COMPOUNDS NOVO NORDISK A/S (DK) 2024-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209028-A1 CNP COMPOUNDS NPPA, NPR1, NPR3 ACE 475/4885REN 138/4885CTSD 876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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