Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27623239 | 0.90 | MAPT (0.46) | PTGS2ALDH1A1MAPTHSD17B10DDB1 | |
| SCHEMBL62940 | 0.90 | MAPT (0.46) | PTGS2ALDH1A1MAPTHSD17B10DDB1 | |
| Alanine SCHEMBL6904183 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MAPTHSD17B10MAOAMAOB | |
| SCHEMBL9864475 | 0.72 | MAPT (0.38) | ALDH1A1MAPTHSD17B10MGLLDDB1 | |
| SCHEMBL9701179 | 0.71 | TDP2 (0.35) | ALDH1A1MAPTHSD17B10TDP2MGLL | |
| SCHEMBL22498758 | 0.68 | CRBN (0.35) | ALDH1A1MAPTDDB1CRBNCHEK1 | |
| SCHEMBL9751662 | 0.68 | CRBN (0.35) | ALDH1A1MAPTHSD17B10DDB1CRBN | |
| SCHEMBL2001787 | 0.67 | ENPP2 (0.57) | FAAHMGLLDDB1CRBNEPHX2 | |
| SCHEMBL9751620 | 0.67 | CRBN (0.43) | ALDH1A1MAPTHSD17B10DDB1CRBN | |
| Biphenyl SCHEMBL7154019 | 0.63 | CRBN (0.58) | ALDH1A1MAPTHSD17B10TDP2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101863834-B | Preparation method of S-carboxymethyl-5,5-diphenyl-2-thiohydantoin | UNIV BOHAI | 2012-10-10 | — | — | CN | claimed |
| CN-101863835-B | Synthesis method of S-substituted-5,5-diphenyl-2-thiohydantoin derivatives | UNIV BOHAI | 2012-10-10 | — | — | CN | claimed |
| CN-101863836-B | Method for preparing 5,5-diphenyl-2-thiohydantoin | UNIV BOHAI | 2012-10-10 | — | — | CN | claimed |
| CN-101863835-A | Synthesis method of S-substituted-5,5-diphenyl-2-thiohydantoin derivatives | UNIV BOHAI | 2010-10-20 | — | — | CN | claimed |
| CN-101863834-A | Preparation method of S-carboxymethyl-5,5-diphenyl-2-thiohydantoin | UNIV BOHAI | 2010-10-20 | — | — | CN | claimed |
| CN-101863836-A | Method for preparing 5,5-diphenyl-2-thiohydantoin | UNIV BOHAI | 2010-10-20 | — | — | CN | claimed |
| CN-101863834-B | Preparation method of S-carboxymethyl-5,5-diphenyl-2-thiohydantoin | UNIV BOHAI | 2012-10-10 | — | — | CN | disclosed |
| CN-101863835-B | Synthesis method of S-substituted-5,5-diphenyl-2-thiohydantoin derivatives | UNIV BOHAI | 2012-10-10 | — | — | CN | disclosed |
| CN-101863836-B | Method for preparing 5,5-diphenyl-2-thiohydantoin | UNIV BOHAI | 2012-10-10 | — | — | CN | disclosed |
| CN-101863835-A | Synthesis method of S-substituted-5,5-diphenyl-2-thiohydantoin derivatives | UNIV BOHAI | 2010-10-20 | — | — | CN | disclosed |
| CN-101863834-A | Preparation method of S-carboxymethyl-5,5-diphenyl-2-thiohydantoin | UNIV BOHAI | 2010-10-20 | — | — | CN | disclosed |
| CN-101863836-A | Method for preparing 5,5-diphenyl-2-thiohydantoin | UNIV BOHAI | 2010-10-20 | — | — | CN | disclosed |
| CN-1074215-A | Mycocidal 2-tetrahydroglyoxaline-5-ketone and 2-tetrahydroglyoxaline-5-40 thione derivatives | RHONE POULENC AGROCHIMIE (FR) | 1993-07-14 | — | — | CN | disclosed |