Butyrolactone

Butyrolactone

SCHEMBL27413620

O.O=C1CCCO1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Butyrolactone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyrolactone SCHEMBL7766294 1.00 CA1 (0.78)
Butyrolactone SCHEMBL27472080 0.97
Butyrolactone SCHEMBL29433925 0.97
Butyrolactone SCHEMBL13481 0.97
SCHEMBL19638361 0.97 CA1 (0.82)
Butyrolactone SCHEMBL9421121 0.97
Butyrolactone SCHEMBL1271043 0.97 CA1 (0.82)
Butyrolactone SCHEMBL27720055 0.97 CA1 (0.82)
Butyrolactone SCHEMBL932283 0.94
Butyrolactone SCHEMBL5387579 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111054392-B Metal-solid acid double-center catalyst and application thereof in preparation of furfuryl alcohol by catalyzing xylose dehydration-hydrogenation 山西大学 2021-02-02 CN claimed
CN-111054392-A Metal-solid acid double-center catalyst and application thereof in preparation of furfuryl alcohol by catalyzing xylose dehydration-hydrogenation 山西大学 2020-04-24 CN claimed
CN-101208398-A Colorful spectral filter grinding fluid composition BASF CO LTD (DE) 2008-06-25 CN claimed
CN-114736092-B Process for separating olefins from mixtures of alkanes and olefins 国家能源投资集团有限责任公司 2024-04-02 CN disclosed
CN-116199556-A Method for separating mixture containing oxygen-containing compound, alkane and alkene 国家能源投资集团有限责任公司 2023-06-02 CN disclosed
CN-111054392-B Metal-solid acid double-center catalyst and application thereof in preparation of furfuryl alcohol by catalyzing xylose dehydration-hydrogenation 山西大学 2021-02-02 CN disclosed
CN-111054392-A Metal-solid acid double-center catalyst and application thereof in preparation of furfuryl alcohol by catalyzing xylose dehydration-hydrogenation 山西大学 2020-04-24 CN disclosed
CN-1816536-B Cannabinoid receptor modulators TAKAEDA CHEMICAL IND LTD 2012-12-26 CN disclosed
CN-101208398-A Colorful spectral filter grinding fluid composition BASF CO LTD (DE) 2008-06-25 CN disclosed
CN-1898225-A Novel alkoxylactones, alkoxylactames and alkoxythiolactames for controlling processes based on microbial interaction HENKEL KGAA (DE) 2007-01-17 CN disclosed
CN-1093859-C Novel indole-2,3-done-3-oxime derivatives NEUROSEARCH AS (DK) 2002-11-06 CN disclosed
CN-1207100-A Novel indole-2,3-done-3-oxime derivatives NEUROSEARCH AS (DK) 1999-02-03 CN disclosed