Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661404 | 0.86 | MTNR1A (0.38) | POLBCYP3A4TSHRMTNR1AMTNR1B | |
| SCHEMBL6962144 | 0.85 | PTGES (0.45) | POLBTSHRMTNR1AMTNR1BHTT | |
| SCHEMBL27449003 | 0.81 | ALDH1A1 (0.50) | POLBTSHRSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1269406 | 0.81 | NAAA (0.51) | TSHRHTTALDH1A1NPC1RAB9A | |
| SCHEMBL7667932 | 0.81 | OPRM1 (0.44) | TSHRMTNR1AMTNR1BHTTSMN1; SMN2 | |
| SCHEMBL7892825 | 0.80 | NAAA (0.54) | HTTALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL4681303 | 0.78 | HPGD (0.45) | POLBMTNR1AMTNR1BHTTSMN1; SMN2 | |
| SCHEMBL7663064 | 0.78 | MTNR1A (0.37) | TSHRMTNR1AMTNR1BHTTALDH1A1 | |
| SCHEMBL19527581 | 0.76 | POLB (0.43) | POLBCYP3A4TSHRMTNR1AMTNR1B | |
| SCHEMBL6639923 | 0.75 | L3MBTL1 (0.40) | CYP3A4TSHRMTNR1AMTNR1BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1097417-A | New heterogeneous ring compound | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-01-18 | — | — | CN | disclosed |