Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | MMP16 | P51512 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229081 | 0.85 | HTR6 (0.48) | HTR6MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2742904 | 0.81 | HTR6 (0.40) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL2742908 | 0.81 | CYP3A4 (0.48) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL2742905 | 0.76 | HTR6 (0.41) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL226516 | 0.72 | HTR6 (0.48) | HTR6MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL15270570 | 0.72 | CA1 (0.43) | BCL2PTGS1PTGS2KMT2AALDH1A1 | |
| SCHEMBL12087024 | 0.69 | GAA (0.69) | HTR6MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL5253420 | 0.68 | BCL2 (0.47) | BCL2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL25797377 | 0.67 | ALOX5 (0.46) | BCL2ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL16495237 | 0.67 | TSHR (0.45) | HTR6PTGDR2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120322973-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120302725-A1 | POLYARYLENE IONOMERS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120296065-A1 | POLYARYLENE IONOMERS MEMBRANES | EI DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120289678-A1 | METHOD OF MAKING POLYARYLENE IONOMERS AND MEMBRANES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120004387-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004387-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | PCBP1, PARG, PARN | MMP2 4596/4885MMP1 4614/4885MMP3 4359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.