Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227808 | 0.85 | KIF18A (0.57) | CYP3A4KIF18ACNR2PGRHTR6 | |
| SCHEMBL2742902 | 0.81 | MMP2 (0.39) | MEN1KMT2AHTR6MAPTALDH1A1 | |
| SCHEMBL2742904 | 0.81 | HTR6 (0.40) | CYP3A4MEN1KMT2AHTR6MAPT | |
| SCHEMBL9820025 | 0.77 | MEN1 (0.57) | CYP3A4MEN1KMT2AHPGDALOX15 | |
| SCHEMBL9840644 | 0.76 | KIF18A (0.51) | CYP3A4MEN1KMT2AKIF18ACNR2 | |
| SCHEMBL2742905 | 0.76 | HTR6 (0.41) | CYP3A4MEN1KMT2AHTR6MAPT | |
| SCHEMBL28416588 | 0.73 | POLB (0.57) | CYP3A4MEN1KMT2AHPGDALOX15 | |
| SCHEMBL9822747 | 0.73 | MEN1 (0.56) | CYP3A4MEN1KMT2AHPGDALOX15 | |
| SCHEMBL228959 | 0.72 | KIF18A (0.57) | CYP3A4HPGDALOX15KIF18ACNR2 | |
| SCHEMBL27493651 | 0.72 | KMT2A (0.58) | CYP3A4MEN1KMT2AHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120322973-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120004387-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004387-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | PCBP1, PARG, PARN | CYP3A4 578/4885MEN1 2936/4885KMT2A 2095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.