Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27673251 | 0.85 | — | — | |
| Boric Acid SCHEMBL28067257 | 0.81 | F11 (0.54) | ABATHDAC3HDAC6NCOR2HRH3 | |
| Phosphoric Acid SCHEMBL27433800 | 0.77 | SMN1; SMN2 (0.50) | CA2TAAR1 | |
| Benzylamine SCHEMBL28106183 | 0.76 | LOXL2 (0.70) | ANPEPERAP2LOXL2TAAR1 | |
| Benzylamine SCHEMBL8108778 | 0.76 | LOXL2 (0.70) | ANPEPERAP2LOXL2TAAR1 | |
| Benzylamine SCHEMBL7933802 | 0.76 | LOXL2 (0.70) | ANPEPERAP2LOXL2TAAR1 | |
| SCHEMBL2574093 | 0.74 | PGK1 (0.55) | ABATHDAC3HDAC6NCOR2ANPEP | |
| Phosphoric Acid SCHEMBL29157454 | 0.74 | ENPP2 (0.58) | ABATANPEPLOXL2NOS3NOS1 | |
| SCHEMBL13538144 | 0.74 | CA2 (0.48) | ABATHDAC3HDAC6NCOR2ANPEP | |
| Phosphoric Acid SCHEMBL27960194 | 0.73 | FDPS (0.43) | ANPEPERAP2CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101842434-A | Polypropylene composition, method of making the same, and articles made therefrom | DOW GLOBAL TECHNOLOGIES INC | 2010-09-22 | — | — | CN | disclosed |
| CN-100516120-C | Olefin block copolymers, production processes of same and use thereof | MITSUI CHEMICALS INC (JP) | 2009-07-22 | — | — | CN | disclosed |
| CN-100453566-C | Ethylene (co) polymers and use thereof | MITSUI CHEMICALS INC (JP) | 2009-01-21 | — | — | CN | disclosed |
| CN-100436492-C | Olefin polymer | MITSUI CHEMICALS INC (JP) | 2008-11-26 | — | — | CN | disclosed |
| CN-101248132-A | Propylene resin composition | MITSUI CHEMICALS INC (JP) | 2008-08-20 | — | — | CN | disclosed |
| CN-100357330-C | Polar group-containing olefin copolymer, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS INC (JP) | 2007-12-26 | — | — | CN | disclosed |
| CN-100335509-C | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS INC (JP) | 2007-09-05 | — | — | CN | disclosed |
| CN-1326892-C | Ethylene copolymer and ethylene/alpha-olefin copolymer composition and propylene polymer composition both containing the ethylene copolymer | MITSUI CHEMICALS INC (JP) | 2007-07-18 | — | — | CN | disclosed |
| CN-1763114-A | Ethylene copolymer and ethylene/alpha-olefin copolymer composition and propylene polymer composition both containing the ethylene copolymer | MITSUI CHEMICALS INC (JP) | 2006-04-26 | — | — | CN | disclosed |
| CN-1737016-A | Polar group-containing olefin copolymer, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS INC (JP) | 2006-02-22 | — | — | CN | disclosed |
| CN-1383433-A | Ethylene-based copolymer, and ethylene/alpha-olefin copolymer composition and propylene-based copolymer composition each containing the same | MITSUI CHEMICALS INC (JP) | 2002-12-04 | — | — | CN | disclosed |
| CN-1362972-A | Olefin polymer and process for producing the same | MITSUI CHEMICALS INC (JP) | 2002-08-07 | — | — | CN | disclosed |
| CN-1344752-A | Modified polyolefine and resin composition containing the same | MITSUI CHEMICALS INC (JP) | 2002-04-17 | — | — | CN | disclosed |
| CN-1342715-A | Polar group-containing olefin copolymer, process for producing the same, thermoplastic resin composition containing the same, and use thereof | MITSUI CHEMICALS INC (JP) | 2002-04-03 | — | — | CN | disclosed |
| CN-1314921-A | Ethylene (co) polymers and their use | MITSUI CHEMICALS INC (JP) | 2001-09-26 | — | — | CN | disclosed |
| CN-1313880-A | Soft syndiotactic polypropylene compositions and shaped products | MITSUI CHEMICALS INC (JP) | 2001-09-19 | — | — | CN | disclosed |
| CN-1300787-A | Propylene ethylene block copolymer, resin composition and blown plastic articles | IDEMITSU PETROCHEMICAL CO (JP) | 2001-06-27 | — | — | CN | disclosed |
| CN-1226906-A | Triblock oligomers, thermoplastic resin compositions, and antifog moldings | MITSUI CHEMICALS INC (JP) | 1999-08-25 | — | — | CN | disclosed |
| CN-1219177-A | Olefin polymerization catalyst and olefin polymerization process, and olefin polymer composition and hot molded product | MITSUI CHEMICALS INC (JP) | 1999-06-09 | — | — | CN | disclosed |
| CN-1209827-A | 'alpha'-olefin/aromatic vinyl copolymer composition and products thereof | MITSUI CHEMICALS INC (JP) | 1999-03-03 | — | — | CN | disclosed |