Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 2/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675702 | 0.87 | CDK8 (0.39) | ALDH1A1CDK8FKBP1AKDM4ETSHR | |
| SCHEMBL27655719 | 0.85 | ALDH1A1 (0.34) | ALDH1A1CDK8FKBP1AHMGCRKDM4E | |
| SCHEMBL27757343 | 0.85 | ALDH1A1 (0.34) | ALDH1A1CDK8FKBP1AHMGCRKDM4E | |
| SCHEMBL27675694 | 0.83 | ENO1 (0.32) | ALDH1A1CDK8FKBP1A | |
| SCHEMBL27655729 | 0.79 | ALDH1A1 (0.34) | ALDH1A1CDK8FKBP1AMEN1MAPT | |
| SCHEMBL28294099 | 0.77 | ALDH1A1 (0.35) | ALDH1A1FKBP1AHMGCRMEN1MAPT | |
| SCHEMBL7289702 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HPGDGAATSHR | |
| SCHEMBL27609169 | 0.75 | ALDH1A1 (0.40) | ALDH1A1FKBP1ATSHRMEN1KMT2A | |
| SCHEMBL27655761 | 0.74 | FKBP1A (0.39) | ALDH1A1FKBP1AKDM4E | |
| SCHEMBL28759832 | 0.74 | L3MBTL1 (0.41) | FKBP1AGAAMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1098849-C | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 2003-01-15 | — | — | CN | disclosed |
| CN-1227225-A | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 1999-09-01 | — | — | CN | disclosed |