Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655719 | 0.93 | ALDH1A1 (0.34) | CDK8POLBKDM4ETSHRALDH1A1 | |
| SCHEMBL27757343 | 0.93 | ALDH1A1 (0.34) | CDK8POLBKDM4ETSHRALDH1A1 | |
| SCHEMBL27675694 | 0.91 | ENO1 (0.32) | CDK8POLBALDH1A1FKBP1ASPHK1 | |
| SCHEMBL27445707 | 0.87 | ALDH1A1 (0.34) | CDK8KDM4ETSHRALDH1A1FKBP1A | |
| SCHEMBL27655729 | 0.84 | ALDH1A1 (0.34) | CDK8POLBALDH1A1FKBP1ABCHE | |
| SCHEMBL28294099 | 0.82 | ALDH1A1 (0.35) | ALDH1A1FKBP1AKMT2A | |
| SCHEMBL27655761 | 0.79 | FKBP1A (0.39) | KDM4ENAAAALDH1A1FKBP1A | |
| SCHEMBL28759832 | 0.79 | L3MBTL1 (0.41) | FKBP1ABCHEKMT2A | |
| SCHEMBL27842168 | 0.78 | ENO1 (0.33) | ALDH1A1FKBP1ACYP2D6KMT2A | |
| SCHEMBL27841989 | 0.78 | ENO1 (0.33) | ALDH1A1FKBP1ACYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1968954-A | Thienopyridine Derivatives | SANKYO CO (JP) | 2007-05-23 | — | — | CN | disclosed |