Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17411215 | 0.97 | ACHE (0.40) | ACHESIRT2SIRT1TGM2 | |
| SCHEMBL16013473 | 0.97 | ACHE (0.40) | ACHESIRT2SIRT1TGM2 | |
| SCHEMBL18532395 | 0.91 | ACHE (0.39) | ACHEEPHX2 | |
| SCHEMBL17411108 | 0.90 | ACHE (0.37) | ACHETGM2 | |
| SCHEMBL17411140 | 0.89 | ACHE (0.34) | ACHESIRT2SIRT1TGM2 | |
| SCHEMBL16013190 | 0.84 | TGM2 (0.43) | SIRT2SIRT1TGM2 | |
| SCHEMBL13148035 | 0.84 | ACHE (0.59) | ACHESIRT2SIRT1SIRT3EPHX2 | |
| SCHEMBL3695872 | 0.84 | ACHE (0.59) | ACHESIRT2SIRT1SIRT3EPHX2 | |
| SCHEMBL3699964 | 0.84 | ACHE (0.59) | ACHESIRT2SIRT1SIRT3EPHX2 | |
| SCHEMBL30354527 | 0.81 | ACHE (0.60) | ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964224-B1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2024-07-03 | — | — | EP | disclosed |