Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17411215 | 1.00 | ACHE (0.40) | ACHETGM2SIRT2SIRT1KMT2A | |
| SCHEMBL27446533 | 0.97 | ACHE (0.43) | ACHETGM2SIRT2SIRT1 | |
| SCHEMBL18532395 | 0.94 | ACHE (0.39) | ACHEPOLB | |
| SCHEMBL17411108 | 0.93 | ACHE (0.37) | ACHETGM2 | |
| SCHEMBL17411140 | 0.92 | ACHE (0.34) | ACHETGM2SIRT2SIRT1 | |
| SCHEMBL16013190 | 0.87 | TGM2 (0.43) | TGM2SIRT2SIRT1 | |
| SCHEMBL25176590 | 0.82 | KMT2A (0.45) | ACHETGM2SIRT2SIRT1KMT2A | |
| SCHEMBL25176589 | 0.82 | KMT2A (0.45) | ACHETGM2SIRT2SIRT1KMT2A | |
| SCHEMBL3695872 | 0.82 | ACHE (0.59) | ACHESIRT2SIRT1 | |
| SCHEMBL13148035 | 0.82 | ACHE (0.59) | ACHESIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503553-B2 | Biodegradable drug-polymer conjugate | POLYACTIVA PTY LTD (AU) | 2025-12-23 | — | — | US | disclosed |
| US-20240247106-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | POLYACTIVA PTY LTD (AU) | 2024-07-25 | — | — | US | disclosed |
| EP-2964224-B1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2024-07-03 | — | — | EP | disclosed |
| US-11787906-B2 | Biodegradable drug-polymer conjugate | POLYACTIVA PTY LTD (AU) | 2023-10-17 | — | — | US | disclosed |
| US-11696955-B2 | Drug-polymer conjugate | POLYACTIVA PTY LTD (AU) | 2023-07-11 | — | — | US | disclosed |
| US-20220401455-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | POLYACTIVA PTY LTD (AU) | 2022-12-22 | — | — | US | disclosed |
| US-20220226483-A1 | DRUG-POLYMER CONJUGATE | POLYACTIVA PTY LTD (AU) | 2022-07-21 | — | — | US | disclosed |
| US-11207417-B2 | Drug-polymer conjugate | POLYACTIVA PTY LTD (AU) | 2021-12-28 | — | — | US | disclosed |
| WO-2021051149-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | POLYACTIVA PTY LTD (AU) | 2021-03-25 | — | — | WO | disclosed |
| US-10758626-B2 | Polymer conjugate comprising a bioactive agent | POLYACTIVA PTY LTD (AU) | 2020-09-01 | — | — | US | disclosed |
| US-20170216308-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2017-08-03 | — | — | US | disclosed |
| US-20170182173-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2017-06-29 | — | — | US | disclosed |
| US-20170182173-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2017-06-29 | — | — | US | disclosed |
| WO-2017041142-A1 | POLYMER CONJUGATE COMPRISING A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2017-03-16 | — | — | WO | disclosed |
| US-9572892-B2 | Polymer conjugate for delivery of a bioactive agent | POLYACTIVA PTY LTD (AU) | 2017-02-21 | — | — | US | disclosed |
| US-9572892-B2 | Polymer conjugate for delivery of a bioactive agent | POLYACTIVA PTY LTD (AU) | 2017-02-21 | — | — | US | disclosed |
| EP-2964224-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | Polyactiva Pty Ltd (AU) | 2016-01-13 | — | — | EP | disclosed |
| US-20160000929-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2016-01-07 | — | — | US | disclosed |
| US-20160000929-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2016-01-07 | — | — | US | disclosed |
| WO-2014134689-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11207417-B2 | Drug-polymer conjugate | PTGDR, PTGDR2, PTGER3 | ACHE 3335/4885TGM2 1273/4885SIRT2 2719/4885 |
| US-20240247106-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | ADRB3, PTGER3, CHRNE | ACHE 338/4885TGM2 3043/4885SIRT2 4074/4885 |
| US-11696955-B2 | Drug-polymer conjugate | PTGDR, PTGDR2, PTGER3 | ACHE 3335/4885TGM2 1273/4885SIRT2 2719/4885 |
| US-20220401455-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | PTGER1, PTGDR, F12 | ACHE 949/4885TGM2 3081/4885SIRT2 4157/4885 |
| US-10758626-B2 | Polymer conjugate comprising a bioactive agent | MSN, PAM, PARG | ACHE 393/4885TGM2 3656/4885SIRT2 2903/4885 |
| US-20160000929-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | PTGIS, PTGIR, PGF | ACHE 939/4885TGM2 987/4885SIRT2 1093/4885 |
| US-20170216308-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | PTGIS, PTGIR, PGF | ACHE 797/4885TGM2 1012/4885SIRT2 1640/4885 |
| US-20170182173-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | PTGIS, PTGIR, PGF | ACHE 1848/4885TGM2 754/4885SIRT2 1033/4885 |
| US-11787906-B2 | Biodegradable drug-polymer conjugate | ADRB3, PTGER3, CHRM3 | ACHE 351/4885TGM2 3172/4885SIRT2 4113/4885 |
| US-12503553-B2 | Biodegradable drug-polymer conjugate | ADRB3, PTGER3, CHRNE | ACHE 338/4885TGM2 3043/4885SIRT2 4074/4885 |
| US-20220226483-A1 | DRUG-POLYMER CONJUGATE | PTGDR, PTGDR2, PTGER3 | ACHE 3335/4885TGM2 1273/4885SIRT2 2719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.