Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16936165 | 0.85 | LMNA (0.32) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL27902176 | 0.76 | CTH (0.33) | LMNABLM | |
| SCHEMBL3337079 | 0.76 | TSHR (0.35) | BLM | |
| SCHEMBL16936167 | 0.75 | NOD1 (0.32) | LMNASLC6A6CYP2C19BLM | |
| SCHEMBL31589297 | 0.75 | HCAR2 (0.35) | LMNABLM | |
| SCHEMBL25175834 | 0.73 | LMNA (0.43) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL7793498 | 0.73 | — | — | |
| SCHEMBL28960605 | 0.72 | ALDH1A1 (0.47) | LMNACYP2C19 | |
| SCHEMBL28888052 | 0.72 | — | — | |
| SCHEMBL11116684 | 0.71 | ALOX15 (0.33) | BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108064173-B | Partial insulin receptor agonists | 默沙东公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112494656-A | Partial insulin receptor agonists | 默沙东公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-108064173-A | Partial insulin receptor agonists | 默沙东公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-1217724-A | Recombinant preparation of calcitonin fragments and their use in the preparation of calcitonin and related analogues | BIONEBRASKA INC (US) | 1999-05-26 | — | — | CN | disclosed |
| CN-1033330-C | Calcium channel blocking polypeptides from the anophelus malabaricus | PFIZER (US) | 1996-11-20 | — | — | CN | disclosed |
| CN-1090289-A | The polypeptide of the blocking-up calcium channel that from theraphosidae aphonopelma, obtains | PFIZER (US) | 1994-08-03 | — | — | CN | disclosed |