SCHEMBL3337079

SCHEMBL3337079

NC(=O)C[C@H](N)C(=O)OCCO

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.35
▸ SLC7A5 Q01650 1/20 0.33
▸ ALOX15 P16050 1/20 0.31
▸ BLM P54132 1/20 0.31
▸ PMP22 Q01453 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7793498 0.88 — —
SCHEMBL27902176 0.83 CTH (0.33) ALOX15BLMPMP22KMT2A
SCHEMBL14742382 0.83 TSHR (0.35) TSHRSLC7A5
SCHEMBL3453970 0.83 SLC7A5 (0.36) TSHRSLC7A5
SCHEMBL11116684 0.82 ALOX15 (0.33) ALOX15BLMPMP22KMT2A
SCHEMBL31589297 0.81 HCAR2 (0.35) TSHRALOX15BLMPMP22KMT2A
SCHEMBL28051778 0.79 TSHR (0.39) TSHRSLC7A5
SCHEMBL398286 0.79 ALOX15 (0.52) TSHRSLC7A5ALOX15BLMPMP22
SCHEMBL28960605 0.78 ALDH1A1 (0.47) TSHR
SCHEMBL28888052 0.78 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071616-B Streptavidin muteins and methods of use thereof IBA股份有限公司 2023-09-19 — — CN claimed
US-20260125614-A1 IONIZABLE CATIONIC LIPIDS AKAGERA MEDICINES, INC. (US) 2026-05-07 — — US disclosed
US-12606773-B2 Ionizable cationic lipids AKAGERA MEDICINES, INC. (US) 2026-04-21 — — US disclosed
US-20260083674-A1 OXAZOLIDINONE LIPOSOME COMPOSITIONS AKAGERA MEDICINES, INC. (US) 2026-03-26 — — US disclosed
US-20260077038-A1 LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS AND METHODS OF USE THEREOF AKAGERA MEDICINES, INC. (US) 2026-03-19 — — US disclosed
US-12577219-B2 Macrolide brefeldin a ester derivatives and use thereof OCEAN UNIVERSITY OF CHINA (CN) 2026-03-17 — — US disclosed
US-20260069684-A1 LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS AND METHODS OF USE THEREOF AKAGERA MEDICINES, INC. (US) 2026-03-12 — — US disclosed
US-20260055335-A1 IONIZABLE CATIONIC LIPID COMPOUNDS AKAGERA MEDICINES, INC. (US) 2026-02-26 — — US disclosed
US-12522590-B2 Brefeldin a derivatives, preparation method and use thereof OCEAN UNIVERSITY OF CHINA (CN) 2026-01-13 — — US disclosed
US-20260007741-A1 LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS AND VACCINES AKAGERA MEDICINES, INC. (US) 2026-01-08 — — US disclosed
US-20040254352-A1 Lipid-polymer-conjugates YAMANOUCHI EUROPE B.V. (NL) 2004-12-16 — — US disclosed
US-20040241222-A1 Lipid-polymer-conjugates compositions ASTELLAS PHARMA EUROPE B.V. (NL) 2004-12-02 — — US disclosed
EP-1392756-A2 LIPID-POLYMER-CONJUGATES Yamanouchi Europe B.V. (NL) 2004-03-03 — — EP disclosed
EP-1392755-A1 LIPID-POLYMER-CONJUGATES COMPOSITIONS YAMANOUCHI EUROPE B.V. (NL) 2004-03-03 — — EP disclosed
CN-1135235-C method and kit for extracting prion protein ��������ũҵ�� 2004-01-21 — — CN disclosed
WO-2002098951-A2 LIPID-POLYMER-CONJUGATES YAMANOUCHI EUROPE B.V. (NL) 2002-12-12 — — WO disclosed
WO-2002098952-A1 LIPID-POLYMER-CONJUGATES COMPOSITIONS YAMANOUCHI EUROPE B.V. (NL) 2002-12-12 — — WO disclosed
CN-1342266-A Method and kit for extracting prion protein US AGRICULTURE (US) 2002-03-27 — — CN disclosed
CN-1230990-A Recombination of polynucleotide sequences using random or defined primers CALIFORNIA INST OF TECHN (US) 1999-10-06 — — CN disclosed
CN-1038748-C Method for preparing sulfonamide fibrinogen receptor antagonists MERCK & CO INC (US) 1998-06-17 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069684-A1 LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS AND METHODS OF USE THEREOF PHOSPHO1, PLTP, SGMS1 TSHR 4047/4885SLC7A5 117/4885ALOX15 736/4885
US-20040254352-A1 Lipid-polymer-conjugates PARG, GLUL, PARN TSHR 3338/4885SLC7A5 17/4885ALOX15 1412/4885
US-20260007741-A1 LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS AND VACCINES TLR9, TLR3, TLR8 TSHR 3557/4885SLC7A5 1104/4885ALOX15 759/4885
US-20040241222-A1 Lipid-polymer-conjugates compositions PHOSPHO1, PARG, GLUL TSHR 3051/4885SLC7A5 10/4885ALOX15 2551/4885
US-20260077038-A1 LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS AND METHODS OF USE THEREOF PHOSPHO1, LNPK, SGMS2 TSHR 3848/4885SLC7A5 122/4885ALOX15 2875/4885
US-12577219-B2 Macrolide brefeldin a ester derivatives and use thereof BCL6, BCL6B, BCL3 TSHR 1251/4885SLC7A5 2339/4885ALOX15 3540/4885
US-20260125614-A1 IONIZABLE CATIONIC LIPIDS CPT2, NPC1L1, PNPLA2 TSHR 2879/4885SLC7A5 234/4885ALOX15 237/4885
US-12606773-B2 Ionizable cationic lipids NPC1L1, MCOLN1, SLC22A4 TSHR 3171/4885SLC7A5 193/4885ALOX15 1321/4885
US-20260055335-A1 IONIZABLE CATIONIC LIPID COMPOUNDS CD4, LDLR, CD2BP2 TSHR 664/4885SLC7A5 346/4885ALOX15 259/4885
US-20260083674-A1 OXAZOLIDINONE LIPOSOME COMPOSITIONS TBCD, SLK, PLA2G2C TSHR 2733/4885SLC7A5 726/4885ALOX15 3482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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